Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 1503208..1503808 Replicon chromosome
Accession NZ_CP114590
Organism Salinivibrio kushneri strain TGB19

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag O4546_RS07085 Protein ID WP_077523530.1
Coordinates 1503208..1503531 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag O4546_RS07090 Protein ID WP_077523528.1
Coordinates 1503524..1503808 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O4546_RS07075 (O4546_07075) 1498538..1501984 - 3447 WP_269586717.1 type I-F CRISPR-associated helicase Cas3f -
O4546_RS07080 (O4546_07080) 1501981..1502952 - 972 WP_269586718.1 type I-F CRISPR-associated endonuclease Cas1f -
O4546_RS07085 (O4546_07085) 1503208..1503531 + 324 WP_077523530.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O4546_RS07090 (O4546_07090) 1503524..1503808 + 285 WP_077523528.1 helix-turn-helix transcriptional regulator Antitoxin
O4546_RS07095 (O4546_07095) 1504880..1505149 + 270 WP_077658679.1 TIGR03643 family protein -
O4546_RS07100 (O4546_07100) 1505475..1506653 - 1179 WP_269586719.1 amidase family protein -
O4546_RS07105 (O4546_07105) 1506828..1507994 - 1167 WP_269586720.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(32-87)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12130.28 Da        Isoelectric Point: 10.2189

>T266755 WP_077523530.1 NZ_CP114590:1503208-1503531 [Salinivibrio kushneri]
MHWNIVFYRGVEESILNMPPKIQARMLKLLELIEKHGANLGPPHTESIGNGLFEIRAKAKEGIGRSLFCYLDGPNIYILH
AFVKKSQKTPKRDLALATGRMKEVKSE

Download         Length: 324 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10442.99 Da        Isoelectric Point: 9.5614

>AT266755 WP_077523528.1 NZ_CP114590:1503524-1503808 [Salinivibrio kushneri]
VNSLQALKARALQNPDVKQAYDELAPEFELIDMLLSMRKQAGLTQQQVAERMGTKEGNISRLEKGKSNPTLKTLISYAKA
CNCTLNFGYKHASN

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References