Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2349982..2350688 Replicon chromosome
Accession NZ_CP114551
Organism Xylella fastidiosa subsp. pauca strain OLI17A

Toxin (Protein)


Gene name mqsR Uniprot ID Q9PAL4
Locus tag O4443_RS10790 Protein ID WP_010894925.1
Coordinates 2349982..2350284 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag O4443_RS10795 Protein ID WP_060872143.1
Coordinates 2350287..2350688 (+) Length 134 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O4443_RS10765 (O4443_10765) 2345140..2346318 - 1179 WP_023907007.1 phage tail sheath family protein -
O4443_RS10770 (O4443_10770) 2346383..2347975 - 1593 WP_282454408.1 hypothetical protein -
O4443_RS10775 (O4443_10775) 2347983..2348540 - 558 WP_031336758.1 phage tail protein I -
O4443_RS10780 (O4443_10780) 2348533..2349426 - 894 WP_088372108.1 baseplate J/gp47 family protein -
O4443_RS10785 (O4443_10785) 2349426..2349788 - 363 WP_233242664.1 GPW/gp25 family protein -
O4443_RS10790 (O4443_10790) 2349982..2350284 + 303 WP_010894925.1 type II toxin-antitoxin system MqsR family toxin Toxin
O4443_RS10795 (O4443_10795) 2350287..2350688 + 402 WP_060872143.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
O4443_RS10800 (O4443_10800) 2350757..2351344 - 588 WP_088372104.1 phage baseplate assembly protein V -
O4443_RS10805 (O4443_10805) 2351341..2351883 - 543 WP_023907017.1 hypothetical protein -
O4443_RS10810 (O4443_10810) 2351859..2352380 - 522 WP_010893241.1 hypothetical protein -
O4443_RS10815 (O4443_10815) 2352377..2352700 - 324 WP_042462902.1 hypothetical protein -
O4443_RS10820 (O4443_10820) 2352700..2352960 - 261 WP_010893239.1 hypothetical protein -
O4443_RS10825 (O4443_10825) 2352978..2354858 - 1881 WP_088372102.1 phage major capsid protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2339433..2372770 33337


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-99)

Antitoxin

(74-127)


Sequences


Toxin        


Download         Length: 101 a.a.        Molecular weight: 10958.74 Da        Isoelectric Point: 8.0251

>T266719 WP_010894925.1 NZ_CP114551:2349982-2350284 [Xylella fastidiosa subsp. pauca]
MEKGTPHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCTVVLALTSADFYKSMTTYADHTVFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL

Download         Length: 303 bp


Antitoxin


Download         Length: 134 a.a.        Molecular weight: 15004.12 Da        Isoelectric Point: 7.1650

>AT266719 WP_060872143.1 NZ_CP114551:2350287-2350688 [Xylella fastidiosa subsp. pauca]
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSF

Download         Length: 402 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB Q9PAL4


Antitoxin

Source ID Structure

References