Detailed information of TA system TA026671

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1425800..1425980
• Replicon: chromosome
• Accession: NC_017342
• Organism: Staphylococcus aureus subsp. aureus TCH60

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: HMPREF0772_RS15125
• Protein ID: WP_001801861.1
• Coordinates: 1425885..1425980 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1425800..1425857 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HMPREF0772_RS07240	1421214..1423634	-	2421	WP_000182551.1	polysaccharide lyase 8 family protein	-
HMPREF0772_RS07245	1424159..1424601	+	443	Protein_1338	DUF1433 domain-containing protein	-
HMPREF0772_RS07250	1424601..1425044	+	444	WP_000731421.1	DUF1433 domain-containing protein	-
HMPREF0772_RS14630	1425044..1425486	+	443	Protein_1340	DUF1433 domain-containing protein	-
HMPREF0772_RS07260	1425661..1425762	-	102	WP_001791232.1	hypothetical protein	-
-	1425800..1425857	+	58	-	-	Antitoxin
HMPREF0772_RS15125	1425885..1425980	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
HMPREF0772_RS07265	1426431..1426877	+	447	WP_000747804.1	DUF1433 domain-containing protein	-
HMPREF0772_RS07270	1427070..1427639	+	570	WP_000125075.1	ImmA/IrrE family metallo-endopeptidase	-
HMPREF0772_RS07275	1427639..1429006	+	1368	WP_001093573.1	FRG domain-containing protein	-
HMPREF0772_RS07280	1429155..1429727	-	573	WP_000414222.1	hypothetical protein	-
HMPREF0772_RS07285	1429825..1430169	-	345	WP_000627550.1	DUF3969 family protein	-
HMPREF0772_RS07290	1430210..1430836	-	627	WP_000669038.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk / hysA	1396045..1433395	37350

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T26671 WP_001801861.1 NC_017342:c1425980-1425885 [Staphylococcus aureus subsp. aureus TCH60]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T26671 NC_017342:c1425980-1425885 [Staphylococcus aureus subsp. aureus TCH60]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT26671 NC_017342:1425800-1425857 [Staphylococcus aureus subsp. aureus TCH60]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin