Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2270191..2270897 Replicon chromosome
Accession NZ_CP114549
Organism Xylella fastidiosa subsp. pauca strain ALM4

Toxin (Protein)


Gene name mqsR Uniprot ID Q9PAL4
Locus tag O4444_RS10280 Protein ID WP_010894925.1
Coordinates 2270191..2270493 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag O4444_RS10285 Protein ID WP_060872143.1
Coordinates 2270496..2270897 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O4444_RS10255 (O4444_10255) 2265349..2266527 - 1179 WP_023907007.1 phage tail sheath family protein -
O4444_RS10260 (O4444_10260) 2266592..2268184 - 1593 WP_282459574.1 hypothetical protein -
O4444_RS10265 (O4444_10265) 2268192..2268749 - 558 WP_282459575.1 phage tail protein I -
O4444_RS10270 (O4444_10270) 2268742..2269635 - 894 WP_023907762.1 baseplate J/gp47 family protein -
O4444_RS10275 (O4444_10275) 2269635..2269997 - 363 WP_233242664.1 GPW/gp25 family protein -
O4444_RS10280 (O4444_10280) 2270191..2270493 + 303 WP_010894925.1 type II toxin-antitoxin system MqsR family toxin Toxin
O4444_RS10285 (O4444_10285) 2270496..2270897 + 402 WP_060872143.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
O4444_RS10290 (O4444_10290) 2270966..2271553 - 588 WP_088372104.1 phage baseplate assembly protein V -
O4444_RS10295 (O4444_10295) 2271550..2272092 - 543 WP_023907017.1 hypothetical protein -
O4444_RS10300 (O4444_10300) 2272068..2272589 - 522 WP_010893241.1 hypothetical protein -
O4444_RS10305 (O4444_10305) 2272586..2272909 - 324 WP_042462902.1 hypothetical protein -
O4444_RS10310 (O4444_10310) 2272909..2273169 - 261 WP_010893239.1 hypothetical protein -
O4444_RS10315 (O4444_10315) 2273187..2275067 - 1881 WP_088372102.1 phage major capsid protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2259642..2302475 42833


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-99)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-127)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 10958.74 Da        Isoelectric Point: 8.0251

>T266694 WP_010894925.1 NZ_CP114549:2270191-2270493 [Xylella fastidiosa subsp. pauca]
MEKGTPHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCTVVLALTSADFYKSMTTYADHTVFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL

Download         Length: 303 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 15004.12 Da        Isoelectric Point: 7.1650

>AT266694 WP_060872143.1 NZ_CP114549:2270496-2270897 [Xylella fastidiosa subsp. pauca]
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSF

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q9PAL4

Antitoxin

Source ID Structure

References