Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprG-sprF/- |
Location | 1116972..1117250 | Replicon | chromosome |
Accession | NC_017342 | ||
Organism | Staphylococcus aureus subsp. aureus TCH60 |
Toxin (Protein)
Gene name | SprG3 | Uniprot ID | - |
Locus tag | HMPREF0772_RS05490 | Protein ID | WP_073392962.1 |
Coordinates | 1116972..1117076 (+) | Length | 35 a.a. |
Antitoxin (RNA)
Gene name | SprF3 | ||
Locus tag | - | ||
Coordinates | 1117072..1117250 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HMPREF0772_RS05480 | 1113768..1114550 | + | 783 | WP_000908186.1 | ABC transporter ATP-binding protein | - |
HMPREF0772_RS05485 | 1114618..1115475 | + | 858 | WP_000370937.1 | Cof-type HAD-IIB family hydrolase | - |
HMPREF0772_RS14495 | 1116134..1116292 | - | 159 | WP_001792784.1 | hypothetical protein | - |
HMPREF0772_RS05490 | 1116972..1117076 | + | 105 | WP_073392962.1 | hypothetical protein | Toxin |
- | 1117072..1117250 | - | 179 | - | - | Antitoxin |
HMPREF0772_RS05495 | 1117518..1118609 | - | 1092 | WP_000495684.1 | hypothetical protein | - |
HMPREF0772_RS05500 | 1118875..1119855 | - | 981 | WP_000019741.1 | CDF family zinc efflux transporter CzrB | - |
HMPREF0772_RS05505 | 1119857..1120177 | - | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
HMPREF0772_RS05510 | 1120329..1120994 | + | 666 | WP_001024099.1 | SDR family oxidoreductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3920.80 Da Isoelectric Point: 5.5724
>T26662 WP_073392962.1 NC_017342:1116972-1117076 [Staphylococcus aureus subsp. aureus TCH60]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T26662 NC_017342:1116972-1117076 [Staphylococcus aureus subsp. aureus TCH60]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
Antitoxin
Download Length: 179 bp
>AT26662 NC_017342:c1117250-1117072 [Staphylococcus aureus subsp. aureus TCH60]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|