Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1116972..1117250 Replicon chromosome
Accession NC_017342
Organism Staphylococcus aureus subsp. aureus TCH60

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag HMPREF0772_RS05490 Protein ID WP_073392962.1
Coordinates 1116972..1117076 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 1117072..1117250 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HMPREF0772_RS05480 1113768..1114550 + 783 WP_000908186.1 ABC transporter ATP-binding protein -
HMPREF0772_RS05485 1114618..1115475 + 858 WP_000370937.1 Cof-type HAD-IIB family hydrolase -
HMPREF0772_RS14495 1116134..1116292 - 159 WP_001792784.1 hypothetical protein -
HMPREF0772_RS05490 1116972..1117076 + 105 WP_073392962.1 hypothetical protein Toxin
- 1117072..1117250 - 179 - - Antitoxin
HMPREF0772_RS05495 1117518..1118609 - 1092 WP_000495684.1 hypothetical protein -
HMPREF0772_RS05500 1118875..1119855 - 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
HMPREF0772_RS05505 1119857..1120177 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
HMPREF0772_RS05510 1120329..1120994 + 666 WP_001024099.1 SDR family oxidoreductase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T26662 WP_073392962.1 NC_017342:1116972-1117076 [Staphylococcus aureus subsp. aureus TCH60]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T26662 NC_017342:1116972-1117076 [Staphylococcus aureus subsp. aureus TCH60]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGATTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 179 bp

>AT26662 NC_017342:c1117250-1117072 [Staphylococcus aureus subsp. aureus TCH60]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References