Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 831852..832036 Replicon chromosome
Accession NC_017342
Organism Staphylococcus aureus subsp. aureus TCH60

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag HMPREF0772_RS03975 Protein ID WP_000482647.1
Coordinates 831852..831959 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 831976..832036 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HMPREF0772_RS03950 827214..827687 + 474 WP_000456496.1 GyrI-like domain-containing protein -
HMPREF0772_RS03955 827810..829021 - 1212 WP_001191920.1 multidrug effflux MFS transporter -
HMPREF0772_RS03960 829203..829862 - 660 WP_000831298.1 membrane protein -
HMPREF0772_RS03965 829922..831064 - 1143 WP_001176856.1 glycerate kinase -
HMPREF0772_RS03970 831332..831718 + 387 WP_000779351.1 flippase GtxA -
HMPREF0772_RS03975 831852..831959 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 831976..832036 - 61 - - Antitoxin
HMPREF0772_RS03985 832607..834370 + 1764 WP_001064829.1 ABC transporter ATP-binding protein/permease -
HMPREF0772_RS03990 834395..836128 + 1734 WP_000486505.1 ABC transporter ATP-binding protein/permease -
HMPREF0772_RS04000 836359..836526 + 168 Protein_754 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T26658 WP_000482647.1 NC_017342:831852-831959 [Staphylococcus aureus subsp. aureus TCH60]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T26658 NC_017342:831852-831959 [Staphylococcus aureus subsp. aureus TCH60]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT26658 NC_017342:c832036-831976 [Staphylococcus aureus subsp. aureus TCH60]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References