Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2588959..2589143 Replicon chromosome
Accession NC_017341
Organism Staphylococcus aureus subsp. aureus str. JKD6008

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag SAA6008_RS13490 Protein ID WP_000482650.1
Coordinates 2589036..2589143 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2588959..2589019 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAA6008_RS13465 2584489..2584656 - 168 WP_001790576.1 hypothetical protein -
SAA6008_RS13475 2584887..2586620 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
SAA6008_RS13480 2586645..2588408 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2588959..2589019 + 61 - - Antitoxin
SAA6008_RS13490 2589036..2589143 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
SAA6008_RS13495 2589276..2589662 - 387 WP_000779358.1 flippase GtxA -
SAA6008_RS13500 2589930..2591072 + 1143 WP_001176863.1 glycerate kinase -
SAA6008_RS13505 2591132..2591791 + 660 WP_000831298.1 membrane protein -
SAA6008_RS13510 2591973..2593184 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SAA6008_RS13515 2593307..2593780 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T26654 WP_000482650.1 NC_017341:c2589143-2589036 [Staphylococcus aureus subsp. aureus str. JKD6008]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T26654 NC_017341:c2589143-2589036 [Staphylococcus aureus subsp. aureus str. JKD6008]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT26654 NC_017341:2588959-2589019 [Staphylococcus aureus subsp. aureus str. JKD6008]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References