Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2295454..2295671 Replicon chromosome
Accession NC_017341
Organism Staphylococcus aureus subsp. aureus str. JKD6008

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SAA6008_RS11800 Protein ID WP_001802298.1
Coordinates 2295567..2295671 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2295454..2295509 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAA6008_RS11780 2291591..2292256 - 666 WP_001024106.1 SDR family oxidoreductase -
SAA6008_RS11785 2292408..2292728 + 321 WP_000003760.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SAA6008_RS11790 2292730..2293710 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
SAA6008_RS11795 2293976..2295067 + 1092 WP_000495671.1 lytic regulatory protein -
- 2295454..2295509 + 56 - - Antitoxin
SAA6008_RS11800 2295567..2295671 - 105 WP_001802298.1 hypothetical protein Toxin
SAA6008_RS16125 2295832..2296315 - 484 Protein_2245 recombinase family protein -
SAA6008_RS11810 2296358..2297494 - 1137 WP_000115564.1 SAP domain-containing protein -
SAA6008_RS11815 2297783..2297875 + 93 WP_001790138.1 hypothetical protein -
SAA6008_RS11820 2298580..2299437 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
SAA6008_RS11825 2299505..2300287 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T26652 WP_001802298.1 NC_017341:c2295671-2295567 [Staphylococcus aureus subsp. aureus str. JKD6008]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T26652 NC_017341:c2295671-2295567 [Staphylococcus aureus subsp. aureus str. JKD6008]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT26652 NC_017341:2295454-2295509 [Staphylococcus aureus subsp. aureus str. JKD6008]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9


Antitoxin

Download structure file

References