Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 3582349..3583582 Replicon chromosome
Accession NZ_CP114289
Organism Flavobacterium limnophilum strain IMCC36791

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag OZP13_RS14870 Protein ID WP_269240899.1
Coordinates 3582349..3583272 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag OZP13_RS14875 Protein ID WP_281297675.1
Coordinates 3583265..3583582 (-) Length 106 a.a.

Genomic Context

OZP13_RS14845OZP13_RS14855OZP13_RS14860OZP13_RS14865OZP13_RS14885OZP13_RS14890OZP13_RS14895OZP13_RS14905OZP13_RS14910OZP13_RS14915OZP13_RS14850OZP13_RS14870OZP13_RS14875OZP13_RS14880
Location: 3577750..3578622 (873 bp)
Type: Others
Protein ID: WP_269240893.1
Location: 3579805..3580521 (717 bp)
Type: Others
Protein ID: WP_269240896.1
Location: 3580647..3581921 (1275 bp)
Type: Others
Protein ID: WP_269240897.1
Location: 3581912..3582352 (441 bp)
Type: Others
Protein ID: WP_269240898.1
Location: 3584248..3584580 (333 bp)
Type: Others
Protein ID: WP_269240904.1
Location: 3584568..3584888 (321 bp)
Type: Others
Protein ID: WP_269240905.1
Location: 3585032..3585442 (411 bp)
Type: Others
Protein ID: WP_281297676.1
Location: 3585963..3586904 (942 bp)
Type: Others
Protein ID: WP_281297677.1
Location: 3586973..3587581 (609 bp)
Type: Others
Protein ID: WP_269240908.1
Location: 3587713..3588387 (675 bp)
Type: Others
Protein ID: WP_281297678.1
Location: 3578761..3579375 (615 bp)
Type: Others
Protein ID: WP_281297674.1
Location: 3582349..3583272 (924 bp)
Type: Toxin
Protein ID: WP_269240899.1
Location: 3583265..3583582 (318 bp)
Type: Antitoxin
Protein ID: WP_281297675.1
Location: 3583582..3583791 (210 bp)
Type: Others
Protein ID: WP_269240902.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
OZP13_RS148453577750..3578622+873WP_269240893.1AraC family transcriptional regulator-
OZP13_RS148503578761..3579375-615WP_281297674.1hypothetical protein-
OZP13_RS148553579805..3580521+717WP_269240896.1DsbA family oxidoreductase-
OZP13_RS148603580647..3581921+1275WP_269240897.1Y-family DNA polymerase-
OZP13_RS148653581912..3582352+441WP_269240898.1translesion error-prone DNA polymerase V autoproteolytic subunit-
OZP13_RS148703582349..3583272-924WP_269240899.1HipA domain-containing proteinToxin
OZP13_RS148753583265..3583582-318WP_281297675.1HipA N-terminal domain-containing proteinAntitoxin
OZP13_RS148803583582..3583791-210WP_269240902.1helix-turn-helix domain-containing protein-
OZP13_RS148853584248..3584580+333WP_269240904.1type II toxin-antitoxin system RelE/ParE family toxin-
OZP13_RS148903584568..3584888+321WP_269240905.1helix-turn-helix transcriptional regulator-
OZP13_RS148953585032..3585442+411WP_281297676.1hypothetical protein-
OZP13_RS149053585963..3586904+942WP_281297677.1ribose-phosphate pyrophosphokinase-
OZP13_RS149103586973..3587581+609WP_269240908.150S ribosomal protein L25/general stress protein Ctc-
OZP13_RS149153587713..3588387+675WP_281297678.1aminoacyl-tRNA hydrolase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(52-279)

Antitoxin

HipA, N-terminal subdomain 1

(6-99)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 35284.77 Da        Isoelectric Point: 8.8824

>T266453 WP_269240899.1 NZ_CP114289:c3583272-3582349 [Flavobacterium limnophilum]
MNRCPITYELCGTEKYSEKGLRLIAPKLTALNDLPFTAAEQRQEAANRANKLSIQGVQPKLSAVISVVKQQFEIVDQFGN
YIIKPQNDIFLELPENEDVTMKMAKVYGLEVPFHGLVYSKDGSLSYFIKRFDRYSKGKKYATEDFAQLSGNSRDTKYDYT
MEKLVKVIDEFCTFPAIAKADFFKRVLFCFITGNEDMHLKNFSVITKAGKTTLAPVYDFLNSSISIKNPQEELALSLKGK
KSNFKSTELIDYYAKERLELNDKTIDVILSDMNKSVSKWTELVEISFLSDVMKEKYLKLMENRIKRF

Download         Length: 924 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11782.49 Da        Isoelectric Point: 4.6533

>AT266453 WP_281297675.1 NZ_CP114289:c3583582-3583265 [Flavobacterium limnophilum]
MMRKATILVHDKRAGILMEDNAGGYQFTYDDNYEGEPVSLTMPLTAKHYSFAKFPSFFEGLLPEGIMLEGLLKIGKIDKN
DYFSQLVATGNDLVGAVTVKEWKDE

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References