Detailed information of TA system TA026640

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1913885..1914067
• Replicon: chromosome
• Accession: NC_017341
• Organism: Staphylococcus aureus subsp. aureus str. JKD6008

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAA6008_RS16090
• Protein ID: WP_001801861.1
• Coordinates: 1913885..1913980 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1914008..1914067 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAA6008_RS09390	1909545..1910171	+	627	WP_000669046.1	hypothetical protein	-
SAA6008_RS09395	1910212..1910556	+	345	WP_000627551.1	DUF3969 family protein	-
SAA6008_RS09400	1910654..1911205	+	552	WP_000414205.1	hypothetical protein	-
SAA6008_RS09405	1911423..1912064	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
SAA6008_RS09410	1912178..1912363	-	186	WP_000809857.1	hypothetical protein	-
SAA6008_RS09415	1912365..1912541	-	177	WP_000375476.1	hypothetical protein	-
SAA6008_RS09420	1912552..1912935	-	384	WP_000070811.1	hypothetical protein	-
SAA6008_RS09430	1913539..1913682	-	144	WP_001549059.1	transposase	-
SAA6008_RS16090	1913885..1913980	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1914008..1914067	-	60	-	-	Antitoxin
SAA6008_RS09435	1914103..1914204	+	102	WP_001791893.1	hypothetical protein	-
SAA6008_RS15665	1914182..1914358	-	177	Protein_1822	transposase	-
SAA6008_RS09440	1914552..1914929	-	378	WP_001037045.1	DUF1433 domain-containing protein	-
SAA6008_RS09445	1915450..1916679	-	1230	Protein_1824	ATP-binding protein	-
SAA6008_RS09450	1916781..1917953	+	1173	WP_000195429.1	IS256-like element IS256 family transposase	-
SAA6008_RS15675	1918006..1918182	+	177	Protein_1826	DUF1829 domain-containing protein	-
SAA6008_RS15680	1918643..1918851	+	209	Protein_1827	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1916781..1917953	1172

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T26640 WP_001801861.1 NC_017341:1913885-1913980 [Staphylococcus aureus subsp. aureus str. JKD6008]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T26640 NC_017341:1913885-1913980 [Staphylococcus aureus subsp. aureus str. JKD6008]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT26640 NC_017341:c1914067-1914008 [Staphylococcus aureus subsp. aureus str. JKD6008]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin