Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2219663..2219879 Replicon chromosome
Accession NC_017340
Organism Staphylococcus aureus 04-02981

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SA2981_RS11270 Protein ID WP_001802298.1
Coordinates 2219775..2219879 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2219663..2219718 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA2981_RS11250 2215869..2216534 - 666 WP_001024095.1 SDR family oxidoreductase -
SA2981_RS11255 2216686..2217006 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SA2981_RS11260 2217008..2217985 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
SA2981_RS11265 2218251..2219342 + 1092 WP_000495669.1 hypothetical protein -
- 2219663..2219718 + 56 - - Antitoxin
SA2981_RS11270 2219775..2219879 - 105 WP_001802298.1 hypothetical protein Toxin
SA2981_RS14825 2220559..2220717 + 159 WP_001792784.1 hypothetical protein -
SA2981_RS11275 2221375..2222232 - 858 WP_000370923.1 Cof-type HAD-IIB family hydrolase -
SA2981_RS11280 2222300..2223082 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T26632 WP_001802298.1 NC_017340:c2219879-2219775 [Staphylococcus aureus 04-02981]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T26632 NC_017340:c2219879-2219775 [Staphylococcus aureus 04-02981]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT26632 NC_017340:2219663-2219718 [Staphylococcus aureus 04-02981]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References