Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 227610..227831 Replicon chromosome
Accession NZ_CP114130
Organism Escherichia coli strain NJS001

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag N0F11_RS01125 Protein ID WP_001295224.1
Coordinates 227724..227831 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 227610..227675 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0F11_RS01105 (223050) 223050..223952 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
N0F11_RS01110 (223963) 223963..224946 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
N0F11_RS01115 (224943) 224943..225947 + 1005 WP_000107027.1 dipeptide ABC transporter ATP-binding subunit DppF -
N0F11_RS01120 (225977) 225977..227248 - 1272 WP_001301684.1 aromatic amino acid transport family protein -
- (227610) 227610..227675 - 66 NuclAT_14 - Antitoxin
- (227610) 227610..227675 - 66 NuclAT_14 - Antitoxin
- (227610) 227610..227675 - 66 NuclAT_14 - Antitoxin
- (227610) 227610..227675 - 66 NuclAT_14 - Antitoxin
- (227610) 227610..227675 - 66 NuclAT_19 - Antitoxin
- (227610) 227610..227675 - 66 NuclAT_19 - Antitoxin
- (227610) 227610..227675 - 66 NuclAT_19 - Antitoxin
- (227610) 227610..227675 - 66 NuclAT_19 - Antitoxin
N0F11_RS01125 (227724) 227724..227831 + 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
N0F11_RS01130 (227918) 227918..229597 - 1680 WP_000191596.1 cellulose biosynthesis protein BcsG -
N0F11_RS01135 (229594) 229594..229785 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
N0F11_RS01140 (229782) 229782..231353 - 1572 WP_001204920.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
N0F11_RS01145 (231626) 231626..231814 + 189 WP_001063316.1 cellulose biosynthesis protein BcsR -
N0F11_RS01150 (231826) 231826..232578 + 753 Protein_227 cellulose biosynthesis protein BcsQ -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-35)


Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T266286 WP_001295224.1 NZ_CP114130:227724-227831 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp


Antitoxin


Download         Length: 66 bp

>AT266286 NZ_CP114130:c227675-227610 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7


Antitoxin

Download structure file

References