Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4431705..4432359 Replicon chromosome
Accession NZ_CP114115
Organism Pseudomonas sp. GXZC

Toxin (Protein)


Gene name higB Uniprot ID A0A7Y8KJA9
Locus tag OZ428_RS20720 Protein ID WP_038850296.1
Coordinates 4431705..4432055 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID W2E036
Locus tag OZ428_RS20725 Protein ID WP_033896843.1
Coordinates 4432045..4432359 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ428_RS20710 (OZ428_20710) 4428463..4429995 + 1533 WP_269131123.1 NADH-quinone oxidoreductase subunit M -
OZ428_RS20715 (OZ428_20715) 4430003..4431466 + 1464 WP_105698607.1 NADH-quinone oxidoreductase subunit NuoN -
OZ428_RS20720 (OZ428_20720) 4431705..4432055 + 351 WP_038850296.1 toxin Toxin
OZ428_RS20725 (OZ428_20725) 4432045..4432359 + 315 WP_033896843.1 XRE family transcriptional regulator Antitoxin
OZ428_RS20730 (OZ428_20730) 4432395..4432940 - 546 WP_269131124.1 type VI secretion system-associated protein TagF -
OZ428_RS20735 (OZ428_20735) 4432950..4436513 - 3564 WP_269131125.1 type VI secretion system membrane subunit TssM -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13772.64 Da        Isoelectric Point: 9.3833

>T266260 WP_038850296.1 NZ_CP114115:4431705-4432055 [Pseudomonas sp. GXZC]
MDALFIELPAFERHRKDYLSDELFQGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQDDLTPQHKKALKHLLDREIKARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11714.52 Da        Isoelectric Point: 10.6525

>AT266260 WP_033896843.1 NZ_CP114115:4432045-4432359 [Pseudomonas sp. GXZC]
MKREIFSELVEGFDALADERQGKVTLRTHKVHLKNLAPLTAEEVVAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAATLIRLVARFPETVAQLAALG

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Y8KJA9

Antitoxin

Source ID Structure
AlphaFold DB A0A7Y8KJ45

References