Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 4273982..4274586 Replicon chromosome
Accession NZ_CP114115
Organism Pseudomonas sp. GXZC

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OZ428_RS19810 Protein ID WP_269131014.1
Coordinates 4273982..4274296 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OZ428_RS19815 Protein ID WP_177111810.1
Coordinates 4274299..4274586 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ428_RS19790 (OZ428_19790) 4270514..4271185 + 672 WP_269131011.1 response regulator transcription factor -
OZ428_RS19795 (OZ428_19795) 4271267..4271635 + 369 WP_269131012.1 response regulator -
OZ428_RS19800 (OZ428_19800) 4271769..4272968 + 1200 WP_269131013.1 NAD(P)/FAD-dependent oxidoreductase -
OZ428_RS19805 (OZ428_19805) 4273041..4273742 - 702 WP_206542892.1 aquaporin Z -
OZ428_RS19810 (OZ428_19810) 4273982..4274296 + 315 WP_269131014.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OZ428_RS19815 (OZ428_19815) 4274299..4274586 + 288 WP_177111810.1 NadS family protein Antitoxin
OZ428_RS19820 (OZ428_19820) 4274616..4275800 - 1185 WP_269131015.1 sugar transporter -
OZ428_RS19825 (OZ428_19825) 4275924..4276283 - 360 WP_269131016.1 type 1 fimbrial protein -
OZ428_RS19830 (OZ428_19830) 4276370..4277368 - 999 WP_038846999.1 bile acid:sodium symporter family protein -
OZ428_RS19835 (OZ428_19835) 4277455..4278243 + 789 WP_269131017.1 helix-turn-helix transcriptional regulator -
OZ428_RS19840 (OZ428_19840) 4278240..4279475 - 1236 WP_269131018.1 Zn-dependent hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-86)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11786.71 Da        Isoelectric Point: 10.2649

>T266258 WP_269131014.1 NZ_CP114115:4273982-4274296 [Pseudomonas sp. GXZC]
MIFIETPIFTRRVTELMNHDTYLSLQVALMVNPSAGDVIEGTGGIRKIRVASKGHGKRGGARVIYYHFVTASKIALLMIY
SKNEQQDLTNDERKALKAVIEHWR

Download         Length: 315 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10754.41 Da        Isoelectric Point: 8.8278

>AT266258 WP_177111810.1 NZ_CP114115:4274299-4274586 [Pseudomonas sp. GXZC]
MSKFFDELMESVQQMDEIVRGERQPSREFIVDALQVKQIRKATGLTQAKFAAMIDVQIGTLRNWEQGRREPTGPAKALLR
AIHNDPVHVLNALAP

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References