Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 3858204..3858910 Replicon chromosome
Accession NZ_CP114058
Organism Rouxiella chamberiensis strain DSM 28324

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag O1V66_RS17945 Protein ID WP_045048776.1
Coordinates 3858204..3858608 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag O1V66_RS17950 Protein ID WP_045048775.1
Coordinates 3858605..3858910 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1V66_RS17920 (O1V66_17920) 3854342..3854941 - 600 WP_045048780.1 HD domain-containing protein -
O1V66_RS17925 (O1V66_17925) 3855072..3855545 + 474 WP_269127943.1 MarR family transcriptional regulator -
O1V66_RS17930 (O1V66_17930) 3855679..3856104 + 426 WP_045048778.1 organic hydroperoxide resistance protein -
O1V66_RS17935 (O1V66_17935) 3856259..3857944 + 1686 WP_045048777.1 kdo(2)-lipid A phosphoethanolamine 7''-transferase -
O1V66_RS17945 (O1V66_17945) 3858204..3858608 - 405 WP_045048776.1 type II toxin-antitoxin system YafO family toxin Toxin
O1V66_RS17950 (O1V66_17950) 3858605..3858910 - 306 WP_045048775.1 type I toxin-antitoxin system antitoxin YafN Antitoxin
O1V66_RS17955 (O1V66_17955) 3859160..3859450 + 291 WP_045048774.1 muconolactone Delta-isomerase -
O1V66_RS17960 (O1V66_17960) 3859514..3859939 - 426 WP_045048773.1 VOC family protein -
O1V66_RS17965 (O1V66_17965) 3860088..3860975 + 888 WP_045048772.1 LysR family transcriptional regulator -
O1V66_RS17970 (O1V66_17970) 3860972..3862489 - 1518 WP_269128364.1 FAD-dependent oxidoreductase -
O1V66_RS17975 (O1V66_17975) 3862620..3863534 - 915 WP_045048770.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(28-132)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15746.02 Da        Isoelectric Point: 10.0285

>T266236 WP_045048776.1 NZ_CP114058:c3858608-3858204 [Rouxiella chamberiensis]
MSPRVFTSKALRQQLKQEELANLVGDFKSYKASGFPPETFGRDAPYDDERTWPLVRQEEVSHIHLADASTVWHRNILQYR
RTSNKSHLVYCKGSMHNDVFLLIILLQPDAHKMHRDPRHMEKIGLMAQAFRNRF

Download         Length: 405 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11245.63 Da        Isoelectric Point: 4.8129

>AT266236 WP_045048775.1 NZ_CP114058:c3858910-3858605 [Rouxiella chamberiensis]
VNRILTEFTVNVTELRKNPVSYFHADQPVAVLSNNRTAGYMVSAALFEQLIDLISAQQAGRAITAKFKPSAHRLEEITQH
ADAILENLSGKDVSDFEEFEP

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References