Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
Location | 4341207..4341907 | Replicon | chromosome |
Accession | NZ_CP114035 | ||
Organism | Pseudomonas putida strain GMI12077 |
Toxin (Protein)
Gene name | mqsR | Uniprot ID | - |
Locus tag | OZ911_RS20065 | Protein ID | WP_024717923.1 |
Coordinates | 4341611..4341907 (-) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | mqsA | Uniprot ID | A0A8I0Z3K6 |
Locus tag | OZ911_RS20060 | Protein ID | WP_024717924.1 |
Coordinates | 4341207..4341608 (-) | Length | 134 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OZ911_RS20040 (OZ911_20040) | 4336344..4337165 | - | 822 | WP_023048067.1 | transporter substrate-binding domain-containing protein | - |
OZ911_RS20045 (OZ911_20045) | 4337241..4338170 | - | 930 | WP_016488289.1 | FAD-binding protein | - |
OZ911_RS20050 (OZ911_20050) | 4338171..4338920 | - | 750 | WP_016488290.1 | electron transfer flavoprotein subunit beta/FixA family protein | - |
OZ911_RS20055 (OZ911_20055) | 4339472..4341136 | + | 1665 | WP_016488291.1 | electron transfer flavoprotein-ubiquinone oxidoreductase | - |
OZ911_RS20060 (OZ911_20060) | 4341207..4341608 | - | 402 | WP_024717924.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
OZ911_RS20065 (OZ911_20065) | 4341611..4341907 | - | 297 | WP_024717923.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
OZ911_RS20070 (OZ911_20070) | 4342002..4343327 | - | 1326 | WP_023048066.1 | MFS transporter | - |
OZ911_RS20075 (OZ911_20075) | 4343400..4343879 | - | 480 | WP_023048065.1 | hypothetical protein | - |
OZ911_RS20080 (OZ911_20080) | 4344179..4344640 | + | 462 | WP_023048064.1 | azurin | - |
OZ911_RS20085 (OZ911_20085) | 4344678..4345178 | - | 501 | WP_016488297.1 | sigma-70 family RNA polymerase sigma factor | - |
OZ911_RS20090 (OZ911_20090) | 4345409..4346590 | + | 1182 | WP_031312009.1 | efflux RND transporter periplasmic adaptor subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11161.07 Da Isoelectric Point: 9.0375
>T266218 WP_024717923.1 NZ_CP114035:c4341907-4341611 [Pseudomonas putida]
MEKRTPHCPLERVKVLAAARRISPTGAALRGARALGMDYPGMLEVISCLERSDFYKSMTSHMDHRVWQDVYRPLTAFGYV
YLKVSVVDDVLIVSFKEL
MEKRTPHCPLERVKVLAAARRISPTGAALRGARALGMDYPGMLEVISCLERSDFYKSMTSHMDHRVWQDVYRPLTAFGYV
YLKVSVVDDVLIVSFKEL
Download Length: 297 bp
Antitoxin
Download Length: 134 a.a. Molecular weight: 14516.57 Da Isoelectric Point: 4.7550
>AT266218 WP_024717924.1 NZ_CP114035:c4341608-4341207 [Pseudomonas putida]
MRCPVCGGAELAPDVQGMPYSYKGEATVIPDVSGDYCCACGECVLSHDEAMRVSNLMTAFERQVNAAVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA
MRCPVCGGAELAPDVQGMPYSYKGEATVIPDVSGDYCCACGECVLSHDEAMRVSNLMTAFERQVNAAVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA
Download Length: 402 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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