Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4341207..4341907 Replicon chromosome
Accession NZ_CP114035
Organism Pseudomonas putida strain GMI12077

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag OZ911_RS20065 Protein ID WP_024717923.1
Coordinates 4341611..4341907 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A8I0Z3K6
Locus tag OZ911_RS20060 Protein ID WP_024717924.1
Coordinates 4341207..4341608 (-) Length 134 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZ911_RS20040 (OZ911_20040) 4336344..4337165 - 822 WP_023048067.1 transporter substrate-binding domain-containing protein -
OZ911_RS20045 (OZ911_20045) 4337241..4338170 - 930 WP_016488289.1 FAD-binding protein -
OZ911_RS20050 (OZ911_20050) 4338171..4338920 - 750 WP_016488290.1 electron transfer flavoprotein subunit beta/FixA family protein -
OZ911_RS20055 (OZ911_20055) 4339472..4341136 + 1665 WP_016488291.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
OZ911_RS20060 (OZ911_20060) 4341207..4341608 - 402 WP_024717924.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
OZ911_RS20065 (OZ911_20065) 4341611..4341907 - 297 WP_024717923.1 type II toxin-antitoxin system MqsR family toxin Toxin
OZ911_RS20070 (OZ911_20070) 4342002..4343327 - 1326 WP_023048066.1 MFS transporter -
OZ911_RS20075 (OZ911_20075) 4343400..4343879 - 480 WP_023048065.1 hypothetical protein -
OZ911_RS20080 (OZ911_20080) 4344179..4344640 + 462 WP_023048064.1 azurin -
OZ911_RS20085 (OZ911_20085) 4344678..4345178 - 501 WP_016488297.1 sigma-70 family RNA polymerase sigma factor -
OZ911_RS20090 (OZ911_20090) 4345409..4346590 + 1182 WP_031312009.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-97)

Antitoxin

(3-131)


Sequences


Toxin        


Download         Length: 99 a.a.        Molecular weight: 11161.07 Da        Isoelectric Point: 9.0375

>T266218 WP_024717923.1 NZ_CP114035:c4341907-4341611 [Pseudomonas putida]
MEKRTPHCPLERVKVLAAARRISPTGAALRGARALGMDYPGMLEVISCLERSDFYKSMTSHMDHRVWQDVYRPLTAFGYV
YLKVSVVDDVLIVSFKEL

Download         Length: 297 bp


Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14516.57 Da        Isoelectric Point: 4.7550

>AT266218 WP_024717924.1 NZ_CP114035:c4341608-4341207 [Pseudomonas putida]
MRCPVCGGAELAPDVQGMPYSYKGEATVIPDVSGDYCCACGECVLSHDEAMRVSNLMTAFERQVNAAVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References