Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 7701603..7702111 Replicon chromosome
Accession NZ_CP113951
Organism Rhodococcus sp. JS3073

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag OYT95_RS35235 Protein ID WP_128638299.1
Coordinates 7701851..7702111 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OYT95_RS35230 Protein ID WP_268790247.1
Coordinates 7701603..7701854 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OYT95_RS35200 (OYT95_35200) 7696948..7697241 + 294 Protein_6975 ATP-binding protein -
OYT95_RS35205 (OYT95_35205) 7697293..7698006 + 714 WP_268792303.1 LppX_LprAFG lipoprotein -
OYT95_RS35210 (OYT95_35210) 7698003..7699577 + 1575 WP_268790243.1 MFS transporter -
OYT95_RS35215 (OYT95_35215) 7699632..7700033 - 402 WP_268790244.1 hypothetical protein -
OYT95_RS35220 (OYT95_35220) 7700171..7700629 - 459 WP_268790245.1 Clp protease N-terminal domain-containing protein -
OYT95_RS35225 (OYT95_35225) 7701112..7701273 - 162 WP_268790246.1 hypothetical protein -
OYT95_RS35230 (OYT95_35230) 7701603..7701854 + 252 WP_268790247.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
OYT95_RS35235 (OYT95_35235) 7701851..7702111 + 261 WP_128638299.1 Txe/YoeB family addiction module toxin Toxin
OYT95_RS35240 (OYT95_35240) 7702558..7705533 + 2976 WP_268790248.1 UPF0182 family protein -
OYT95_RS35245 (OYT95_35245) 7705633..7706724 + 1092 WP_268790249.1 low temperature requirement protein A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10395.72 Da        Isoelectric Point: 7.3556

>T266189 WP_128638299.1 NZ_CP113951:7701851-7702111 [Rhodococcus sp. JS3073]
VKLVWDESAWEDYVWWQAQDRKIVKRINTLLEDVERNGNDGIGKPEPLKHGFQAYWSRRITDEHRLVYKIVDDQIRIAAC
RYHYGH

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9372.53 Da        Isoelectric Point: 4.5216

>AT266189 WP_268790247.1 NZ_CP113951:7701603-7701854 [Rhodococcus sp. JS3073]
MRTMTYSESRARYAEVLNAVVDDREEIVITRAGHEPVVMVSLDDYESLKETAYLLRSPENARRLLASIDRLESGGGTIRD
LAE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References