Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-DinJ
Location 1823236..1823752 Replicon chromosome
Accession NZ_CP113946
Organism Lactobacillus sp. ESL0677

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag OZX76_RS08910 Protein ID WP_277179578.1
Coordinates 1823236..1823517 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag OZX76_RS08915 Protein ID WP_277179580.1
Coordinates 1823510..1823752 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX76_RS08880 (OZX76_08880) 1819377..1819883 - 507 WP_277179567.1 sigma-70 family RNA polymerase sigma factor -
OZX76_RS08885 (OZX76_08885) 1820114..1820953 - 840 WP_277179569.1 hypothetical protein -
OZX76_RS08890 (OZX76_08890) 1821648..1821803 + 156 WP_277179571.1 hypothetical protein -
OZX76_RS08895 (OZX76_08895) 1822117..1822272 + 156 WP_277179573.1 hypothetical protein -
OZX76_RS08900 (OZX76_08900) 1822586..1822741 + 156 WP_277179575.1 hypothetical protein -
OZX76_RS08905 (OZX76_08905) 1822978..1823121 - 144 WP_277179577.1 hypothetical protein -
OZX76_RS08910 (OZX76_08910) 1823236..1823517 - 282 WP_277179578.1 type II toxin-antitoxin system YafQ family toxin Toxin
OZX76_RS08915 (OZX76_08915) 1823510..1823752 - 243 WP_277179580.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZX76_RS08920 (OZX76_08920) 1823964..1824530 - 567 WP_277179582.1 hypothetical protein -
OZX76_RS08925 (OZX76_08925) 1824954..1825784 - 831 WP_277179584.1 hypothetical protein -
OZX76_RS08930 (OZX76_08930) 1825756..1826277 - 522 WP_277179586.1 hypothetical protein -
OZX76_RS08935 (OZX76_08935) 1826362..1828149 - 1788 WP_277179588.1 SLAP domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(10-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-55)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11409.16 Da        Isoelectric Point: 9.9111

>T266186 WP_277179578.1 NZ_CP113946:c1823517-1823236 [Lactobacillus sp. ESL0677]
MSDFVYKPAFESQFKKHYKKMLKGSKYQAKDFERVYRKLLCNKPLEARYNDYPLINRRPERDLHIKPDWLLIYKYDGEYV
DFINTGSRSDLFK

Download         Length: 282 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9072.28 Da        Isoelectric Point: 4.6412

>AT266186 WP_277179580.1 NZ_CP113946:c1823752-1823510 [Lactobacillus sp. ESL0677]
MTSQVHFRMDSEDKAKFEVVLKNIGLTPGEAFRIFAKKSIEAGGIPFEVTEPAPELQRSIKSRDYVDFDDPEAGLKWLNE

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References