Detailed information of TA system TA026618

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2213141..2213404
• Replicon: chromosome
• Accession: NC_017338
• Organism: Staphylococcus aureus subsp. aureus JKD6159

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: SAA6159_RS11120
• Protein ID: WP_044026008.1
• Coordinates: 2213300..2213404 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF4
Locus tag	-
Coordinates	2213141..2213305 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAA6159_RS11100	2208979..2209644	-	666	WP_001024084.1	SDR family oxidoreductase	-
SAA6159_RS11105	2209796..2210116	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
SAA6159_RS11110	2210118..2211098	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
SAA6159_RS11115	2211364..2212455	+	1092	WP_000495696.1	hypothetical protein	-
-	2213141..2213305	+	165	-	-	Antitoxin
SAA6159_RS11120	2213300..2213404	-	105	WP_044026008.1	hypothetical protein	Toxin
SAA6159_RS14875	2213450..2213668	-	219	Protein_2113	HTH domain-containing protein	-
SAA6159_RS11125	2214248..2214340	+	93	WP_000220903.1	hypothetical protein	-
SAA6159_RS11130	2214469..2215326	-	858	WP_000370915.1	Cof-type HAD-IIB family hydrolase	-
SAA6159_RS11135	2215393..2216175	-	783	WP_000909234.1	ABC transporter ATP-binding protein	-
SAA6159_RS11140	2216402..2218207	-	1806	WP_000334463.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3895.76 Da
• Isoelectric Point: 5.5724

>T26618 WP_044026008.1 NC_017338:c2213404-2213300 [Staphylococcus aureus subsp. aureus JKD6159]
MLLLERISMSDFEILIVVLTIIGLVLISNQDHKK

Nucleotide

• Length: 105 bp

>T26618 NC_017338:c2213404-2213300 [Staphylococcus aureus subsp. aureus JKD6159]
TTGTTACTCCTAGAAAGGATTAGTATGTCTGATTTTGAAATACTGATAGTTGTATTAACAATTATTGGTTTAGTATTGAT
CAGTAATCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 165 bp

>AT26618 NC_017338:2213141-2213305 [Staphylococcus aureus subsp. aureus JKD6159]
GTAGTAAGTAGAAGCAAAAGGTGAAAATCTTTATCTCTTGAAACACAAAAAGGGCAACACTTGGAAACATGTTAGCCTAA
TGAGCCCGTTAAAAAGACAGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Structures

Antitoxin