Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-DinJ
Location 1125073..1125604 Replicon chromosome
Accession NZ_CP113939
Organism Bifidobacterium sp. ESL0690

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag OZX62_RS04510 Protein ID WP_277176830.1
Coordinates 1125314..1125604 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag OZX62_RS04505 Protein ID WP_277176829.1
Coordinates 1125073..1125333 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX62_RS04485 (OZX62_04485) 1120462..1121658 + 1197 WP_277176825.1 type II CAAX endopeptidase family protein -
OZX62_RS04490 (OZX62_04490) 1121787..1122047 - 261 WP_277176826.1 30S ribosomal protein S20 -
OZX62_RS04495 (OZX62_04495) 1122305..1124197 + 1893 WP_277176827.1 translation elongation factor 4 -
OZX62_RS04500 (OZX62_04500) 1124299..1124991 + 693 WP_277176828.1 nitroreductase family protein -
OZX62_RS04505 (OZX62_04505) 1125073..1125333 + 261 WP_277176829.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZX62_RS04510 (OZX62_04510) 1125314..1125604 + 291 WP_277176830.1 type II toxin-antitoxin system YafQ family toxin Toxin
OZX62_RS04515 (OZX62_04515) 1125622..1126926 - 1305 WP_277176831.1 AAA family ATPase -
OZX62_RS04520 (OZX62_04520) 1127104..1127514 - 411 WP_277176832.1 hypothetical protein -
OZX62_RS04525 (OZX62_04525) 1127574..1129271 - 1698 WP_277176833.1 zinc-ribbon domain-containing protein -
OZX62_RS04530 (OZX62_04530) 1129389..1129622 - 234 WP_277176834.1 hypothetical protein -
OZX62_RS04535 (OZX62_04535) 1129699..1130442 - 744 WP_277176835.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(5-94)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11516.42 Da        Isoelectric Point: 10.5771

>T266176 WP_277176830.1 NZ_CP113939:1125314-1125604 [Bifidobacterium sp. ESL0690]
VALQQIERTATFLRQAKQLRRKHYDFDKLEKVIRLLMAQDHEVLRRRYRDHALKGNLRNFRELHIEADWLLIYQIKGDVL
TLVLVETGSHQQLLGK

Download         Length: 291 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9516.84 Da        Isoelectric Point: 5.0323

>AT266176 WP_277176829.1 NZ_CP113939:1125073-1125333 [Bifidobacterium sp. ESL0690]
MNSATIAIRTDPQIKKQAQEVFKGLGLDMSSAINMFLQQTINDRGLPFRPTLSKFEKGVLDAAEGPTRSFDNIDDLMKEL
RGTATD

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References