Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 165390..165913 Replicon chromosome
Accession NZ_CP113929
Organism Bifidobacterium sp. ESL0704

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag OZX64_RS00530 Protein ID WP_277173016.1
Coordinates 165650..165913 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OZX64_RS00525 Protein ID WP_277156667.1
Coordinates 165390..165653 (+) Length 88 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX64_RS00520 (OZX64_00520) 164724..165164 + 441 WP_277173014.1 GNAT family N-acetyltransferase -
OZX64_RS00525 (OZX64_00525) 165390..165653 + 264 WP_277156667.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OZX64_RS00530 (OZX64_00530) 165650..165913 + 264 WP_277173016.1 Txe/YoeB family addiction module toxin Toxin
OZX64_RS00535 (OZX64_00535) 166383..169040 + 2658 WP_277173019.1 AAA family ATPase -
OZX64_RS00540 (OZX64_00540) 169037..170599 + 1563 WP_277173021.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 164724..181499 16775


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-86)

Antitoxin

(1-62)


Sequences


Toxin        


Download         Length: 88 a.a.        Molecular weight: 10190.49 Da        Isoelectric Point: 10.0668

>T266170 WP_277173016.1 NZ_CP113929:165650-165913 [Bifidobacterium sp. ESL0704]
VTYRVAIKNSAKTDLKKLKRSHLQQSFMQVVADLESDPYQPTQSFEKLQPASRGLYSRRINSQHRVVYDVDDRTKTVTIY
AAWSHYE

Download         Length: 264 bp


Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9829.92 Da        Isoelectric Point: 4.2931

>AT266170 WP_277156667.1 NZ_CP113929:165390-165653 [Bifidobacterium sp. ESL0704]
MDTYTPTAARKNLYQILKDVNVQRKPVVISPARGNKDEEAVVVNRADWNSMIETLYLENTGTLATAENRRADNSGTTDID
DIDWDML

Download         Length: 264 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References