Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-DinJ
Location 160247..160775 Replicon chromosome
Accession NZ_CP113915
Organism Bifidobacterium sp. ESL0790

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag OZY47_RS00525 Protein ID WP_277178011.1
Coordinates 160247..160528 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag OZY47_RS00530 Protein ID WP_277178012.1
Coordinates 160521..160775 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZY47_RS00515 (OZY47_00515) 157114..159645 - 2532 WP_277178009.1 BspA family leucine-rich repeat surface protein -
OZY47_RS00520 (OZY47_00520) 159954..160148 - 195 WP_277178010.1 hypothetical protein -
OZY47_RS00525 (OZY47_00525) 160247..160528 - 282 WP_277178011.1 type II toxin-antitoxin system YafQ family toxin Toxin
OZY47_RS00530 (OZY47_00530) 160521..160775 - 255 WP_277178012.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZY47_RS00535 (OZY47_00535) 160981..161403 - 423 WP_277178013.1 hypothetical protein -
OZY47_RS00540 (OZY47_00540) 161471..162307 + 837 WP_277178014.1 hypothetical protein -
OZY47_RS00545 (OZY47_00545) 162449..164224 - 1776 WP_277178016.1 leucine-rich repeat domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 160247..172943 12696


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-81)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11125.04 Da        Isoelectric Point: 10.4608

>T266156 WP_277178011.1 NZ_CP113915:c160528-160247 [Bifidobacterium sp. ESL0790]
MLKSILLTPQFKRDYSSLLKKHYDKTIMQTGINALLQQNKDLLRTRYRDHALKGKWKGYREIHLDGDWLIIYRIEKTELQ
LVLTRTGSHDKLL

Download         Length: 282 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9383.64 Da        Isoelectric Point: 5.6939

>AT266156 WP_277178012.1 NZ_CP113915:c160775-160521 [Bifidobacterium sp. ESL0790]
MSSATIAVRTDPEVKKEAQEVLKSIGLDMSGAINIFLRQVISDQGLPFRPKRDAINARARYEAEHHIGKTFNSVDELMEE
LNNA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References