Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-DinJ
Location 603161..603713 Replicon chromosome
Accession NZ_CP113913
Organism Bifidobacterium sp. ESL0800

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag OZX75_RS02470 Protein ID WP_277146668.1
Coordinates 603423..603713 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag OZX75_RS02465 Protein ID WP_277146667.1
Coordinates 603161..603442 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZX75_RS02445 (OZX75_02445) 599261..599521 - 261 WP_277144664.1 30S ribosomal protein S20 -
OZX75_RS02450 (OZX75_02450) 599784..601676 + 1893 WP_277146664.1 translation elongation factor 4 -
OZX75_RS02455 (OZX75_02455) 601682..602365 + 684 WP_277146665.1 nitroreductase family protein -
OZX75_RS02460 (OZX75_02460) 602671..602904 - 234 WP_277146666.1 hypothetical protein -
OZX75_RS02465 (OZX75_02465) 603161..603442 + 282 WP_277146667.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OZX75_RS02470 (OZX75_02470) 603423..603713 + 291 WP_277146668.1 type II toxin-antitoxin system YafQ family toxin Toxin
OZX75_RS02475 (OZX75_02475) 603784..605154 + 1371 WP_277146669.1 radical SAM family heme chaperone HemW -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-94)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(13-72)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11436.28 Da        Isoelectric Point: 10.5749

>T266153 WP_277146668.1 NZ_CP113913:603423-603713 [Bifidobacterium sp. ESL0800]
VALQRIERSPTFLRQAKALGRKHYDLDKLERVVRVLVNEDKETLRRRYHDHALKGNLSVFRELHIESDWLLIYRVKHETL
TLLLVETGSHRQLLGK

Download         Length: 291 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10321.66 Da        Isoelectric Point: 5.1133

>AT266153 WP_277146667.1 NZ_CP113913:603161-603442 [Bifidobacterium sp. ESL0800]
MSLSASAPKVTRINFRTDTETKEKASSVFAKLGLDMSTALNMFLHQTVVDQALPFRPELSGFEERVLKAASEPTRSFDSV
DDLMEEIRGTSTH

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References