Detailed information of TA system TA266120

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2684835..2685127
• Replicon: chromosome
• Accession: NZ_CP113832
• Organism: Enterococcus faecalis strain M61

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OZF29_RS12995
• Protein ID: WP_021164545.1
• Coordinates: 2684835..2684939 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2684872..2685127 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OZF29_RS12980 (2680038)	2680038..2681030	+	993	WP_002358973.1	biotin--[acetyl-CoA-carboxylase] ligase	-
OZF29_RS12985 (2681294)	2681294..2681932	-	639	WP_002375448.1	lytic polysaccharide monooxygenase	-
OZF29_RS12990 (2682617)	2682617..2684233	+	1617	WP_010778027.1	phosphatase PAP2/LCP family protein	-
- (2684507)	2684507..2684683	-	177	NuclAT_14	-	-
- (2684541)	2684541..2684695	-	155	NuclAT_7	-	-
OZF29_RS12995 (2684835)	2684835..2684939	+	105	WP_021164545.1	putative holin-like toxin	Toxin
- (2684872)	2684872..2685127	-	256	NuclAT_0	-	Antitoxin
OZF29_RS13000 (2685129)	2685129..2688887	-	3759	WP_116495142.1	WxL domain-containing protein	-
- (2689228)	2689228..2689372	-	145	NuclAT_5	-	-
- (2689230)	2689230..2689372	-	143	NuclAT_15	-	-
OZF29_RS13005 (2689483)	2689483..2689626	+	144	WP_002387585.1	putative holin-like toxin	-
- (2689601)	2689601..2689815	-	215	NuclAT_2	-	-
- (2689767)	2689767..2689816	+	50	NuclAT_18	-	-
- (2689558)	2689558..2689817	-	260	NuclAT_13	-	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3813.70 Da
• Isoelectric Point: 10.3686

>T266120 WP_021164545.1 NZ_CP113832:2684835-2684939 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 256 bp

>AT266120 NZ_CP113832:c2685127-2684872 [Enterococcus faecalis]
ATAAAAATGCCCGAGCCTTGAAATAGGAGGCTCAGGCATTTTTTATTGATGGTCTTTTTAGGGTTGTTGTGCTATAATGA
TAAAGAAAAGAGAGATATGCTTCCAACATATCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCAATTTTATTATTTAAA
AATAACCGTGCTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCAATCAAAGCA
ATGGTAAACATACCAA

Structures

Antitoxin