Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 497747..497991 Replicon chromosome
Accession NZ_CP113832
Organism Enterococcus faecalis strain M61

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag OZF29_RS02490 Protein ID WP_021164572.1
Coordinates 497747..497875 (+) Length 43 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 497786..497991 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZF29_RS02480 (493197) 493197..495455 + 2259 WP_116495118.1 DNA helicase PcrA -
OZF29_RS02485 (495581) 495581..497611 + 2031 WP_116495119.1 NAD-dependent DNA ligase LigA -
OZF29_RS02490 (497747) 497747..497875 + 129 WP_021164572.1 putative holin-like toxin Toxin
- (497786) 497786..497991 - 206 NuclAT_10 - Antitoxin
OZF29_RS02495 (498193) 498193..498498 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
OZF29_RS02500 (498498) 498498..499967 + 1470 WP_002361259.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
OZF29_RS02505 (499967) 499967..501397 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
OZF29_RS02510 (501416) 501416..502504 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(7-39)


Sequences

Toxin        


Download         Length: 43 a.a.        Molecular weight: 4495.51 Da        Isoelectric Point: 8.9940

>T266103 WP_021164572.1 NZ_CP113832:497747-497875 [Enterococcus faecalis]
MKGAMFLSVEAALGLMIGFATLVVTIIFVILALVLDNKNNRS

Download         Length: 129 bp

Antitoxin


Download         Length: 206 bp

>AT266103 NZ_CP113832:c497991-497786 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAA
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References