Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-RNAII/-
Location 2933004..2933341 Replicon chromosome
Accession NZ_CP113831
Organism Enterococcus faecalis strain T30

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag OZE10_RS14850 Protein ID WP_002396786.1
Coordinates 2933004..2933147 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2933079..2933341 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OZE10_RS14830 (2928121) 2928121..2928336 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
OZE10_RS14835 (2928475) 2928475..2929467 + 993 WP_023894581.1 biotin--[acetyl-CoA-carboxylase] ligase -
OZE10_RS14840 (2929731) 2929731..2930369 - 639 WP_002378863.1 lytic polysaccharide monooxygenase -
OZE10_RS14845 (2931055) 2931055..2932671 + 1617 WP_047648929.1 phosphatase PAP2/LCP family protein -
OZE10_RS14850 (2933004) 2933004..2933147 + 144 WP_002396786.1 putative holin-like toxin Toxin
- (2933291) 2933291..2933340 + 50 NuclAT_14 - -
- (2933079) 2933079..2933341 - 263 NuclAT_11 - Antitoxin
OZE10_RS14855 (2933342) 2933342..2938033 - 4692 WP_047648930.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T266099 WP_002396786.1 NZ_CP113831:2933004-2933147 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 263 bp

>AT266099 NZ_CP113831:c2933341-2933079 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGAGGGTCGTTGTGCTATA
ATGGTAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCCGTTTCAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References