Detailed information of TA system TA266094

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2854674..2855116
• Replicon: chromosome
• Accession: NZ_CP113831
• Organism: Enterococcus faecalis strain T30

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OZE10_RS14500
• Protein ID: WP_023894767.1
• Coordinates: 2854674..2854778 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2854918..2855116 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OZE10_RS14485 (2849920)	2849920..2850633	-	714	WP_002367455.1	trehalose operon repressor	-
OZE10_RS14490 (2850895)	2850895..2853639	+	2745	WP_047648974.1	glycosyl hydrolase family 65 protein	-
OZE10_RS14495 (2853654)	2853654..2854304	+	651	WP_002354875.1	beta-phosphoglucomutase	-
- (2854359)	2854359..2854499	+	141	NuclAT_10	-	-
- (2854555)	2854555..2854700	+	146	NuclAT_12	-	-
- (2854555)	2854555..2854741	+	187	NuclAT_9	-	-
OZE10_RS14500 (2854674)	2854674..2854778	-	105	WP_023894767.1	putative holin-like toxin	Toxin
- (2854930)	2854930..2855075	+	146	NuclAT_13	-	-
- (2854918)	2854918..2855116	+	199	NuclAT_8	-	Antitoxin
OZE10_RS14505 (2855049)	2855049..2855192	-	144	WP_002392696.1	type I toxin-antitoxin system toxin PepG1	-
OZE10_RS14510 (2855424)	2855424..2856395	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
OZE10_RS14515 (2856570)	2856570..2857007	-	438	WP_002354871.1	peptide-methionine (R)-S-oxide reductase MsrB	-
OZE10_RS14520 (2857140)	2857140..2857694	-	555	WP_002354869.1	Maf family protein	-
OZE10_RS14525 (2857719)	2857719..2859851	-	2133	WP_002378991.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3799.63 Da
• Isoelectric Point: 10.0079

>T266094 WP_023894767.1 NZ_CP113831:c2854778-2854674 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 199 bp

>AT266094 NZ_CP113831:2854918-2855116 [Enterococcus faecalis]
TTTTTAGGGAAATGTGCTATAATGAAAACGAAAAGAGAGATATGCTTCAACATACCTCTCTGATGTAGAGCCGTTTAAGA
CGGTGACCGATTGTATTATTTAAAAATAACCGTACTGGTCAAAGTAGACGGTTATTTTTTATTGTCATTTTTAAGCAATT
TCACAATCAGTGCAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin