Detailed information of TA system TA266087

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2782511..2782995
• Replicon: chromosome
• Accession: NZ_CP113831
• Organism: Enterococcus faecalis strain T30

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: OZE10_RS14155
• Protein ID: WP_075551663.1
• Coordinates: 2782511..2782612 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2782786..2782995 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OZE10_RS14130 (2778036)	2778036..2778989	-	954	WP_002394760.1	siderophore ABC transporter substrate-binding protein	-
OZE10_RS14135 (2779028)	2779028..2779783	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
OZE10_RS14140 (2779780)	2779780..2780745	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
OZE10_RS14145 (2780742)	2780742..2781689	-	948	WP_002359058.1	iron chelate uptake ABC transporter family permease subunit	-
OZE10_RS14150 (2781874)	2781874..2782326	+	453	WP_002359057.1	YueI family protein	-
- (2782352)	2782352..2782562	+	211	NuclAT_6	-	-
- (2782389)	2782389..2782566	+	178	NuclAT_5	-	-
OZE10_RS14155 (2782511)	2782511..2782612	-	102	WP_075551663.1	putative holin-like toxin	Toxin
- (2782786)	2782786..2782995	+	210	NuclAT_7	-	Antitoxin
- (2782820)	2782820..2782999	+	180	NuclAT_4	-	-
OZE10_RS14160 (2782944)	2782944..2783045	-	102	WP_075551663.1	putative holin-like toxin	-
OZE10_RS14165 (2783235)	2783235..2785505	-	2271	WP_002354955.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
OZE10_RS14170 (2785676)	2785676..2786176	+	501	WP_010709949.1	cysteine hydrolase family protein	-
OZE10_RS14175 (2786479)	2786479..2787375	+	897	WP_002354953.1	YitT family protein	-
OZE10_RS14180 (2787426)	2787426..2787824	-	399	WP_002354951.1	glyoxalase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T266087 WP_075551663.1 NZ_CP113831:c2782612-2782511 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 210 bp

>AT266087 NZ_CP113831:2782786-2782995 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin