Detailed information of TA system TA026605

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1884157..1884337
• Replicon: chromosome
• Accession: NC_017338
• Organism: Staphylococcus aureus subsp. aureus JKD6159

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAA6159_RS15120
• Protein ID: WP_001801861.1
• Coordinates: 1884157..1884252 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1884280..1884337 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAA6159_RS09125	1879949..1880575	+	627	WP_000669040.1	hypothetical protein	-
SAA6159_RS09130	1880616..1880957	+	342	WP_000627543.1	DUF3969 family protein	-
SAA6159_RS09135	1881058..1881630	+	573	WP_000414213.1	hypothetical protein	-
SAA6159_RS09140	1881828..1882385	-	558	WP_000864142.1	ImmA/IrrE family metallo-endopeptidase	-
SAA6159_RS09145	1882571..1882756	-	186	WP_000809858.1	hypothetical protein	-
SAA6159_RS09150	1882758..1882934	-	177	WP_000375476.1	hypothetical protein	-
SAA6159_RS09155	1882945..1883328	-	384	WP_000610001.1	hypothetical protein	-
SAA6159_RS09165	1883776..1884012	-	237	WP_000251966.1	IS3 family transposase	-
SAA6159_RS15120	1884157..1884252	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1884280..1884337	-	58	-	-	Antitoxin
SAA6159_RS15125	1884375..1884524	+	150	WP_103245980.1	hypothetical protein	-
SAA6159_RS15225	1884469..1884624	+	156	WP_001215821.1	hypothetical protein	-
SAA6159_RS09170	1885180..1885623	-	444	WP_000731415.1	DUF1433 domain-containing protein	-
SAA6159_RS14755	1885623..1886065	-	443	Protein_1773	DUF1433 domain-containing protein	-
SAA6159_RS09180	1886065..1886508	-	444	WP_000747793.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1883776..1884012	236

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T26605 WP_001801861.1 NC_017338:1884157-1884252 [Staphylococcus aureus subsp. aureus JKD6159]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T26605 NC_017338:1884157-1884252 [Staphylococcus aureus subsp. aureus JKD6159]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT26605 NC_017338:c1884337-1884280 [Staphylococcus aureus subsp. aureus JKD6159]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin