Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1776343..1776938 Replicon chromosome
Accession NZ_CP113783
Organism Pseudoxanthomonas sp. SE1

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag OY559_RS08405 Protein ID WP_277729574.1
Coordinates 1776343..1776624 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OY559_RS08410 Protein ID WP_093297534.1
Coordinates 1776648..1776938 (+) Length 97 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OY559_RS08400 (OY559_08405) 1772314..1775958 + 3645 WP_277729573.1 methylmalonyl-CoA mutase family protein -
OY559_RS08405 (OY559_08410) 1776343..1776624 + 282 WP_277729574.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OY559_RS08410 (OY559_08415) 1776648..1776938 + 291 WP_093297534.1 HigA family addiction module antitoxin Antitoxin
OY559_RS08415 (OY559_08420) 1777136..1777438 + 303 WP_277729575.1 type II toxin-antitoxin system HigB family toxin -
OY559_RS08420 (OY559_08425) 1777435..1777794 + 360 WP_277729576.1 transcriptional regulator -
OY559_RS08425 (OY559_08430) 1777985..1778272 - 288 WP_277729577.1 hypothetical protein -
OY559_RS08430 (OY559_08435) 1778509..1778865 - 357 WP_277729578.1 cell envelope integrity protein TolA -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-93)

Antitoxin

(21-68)


Sequences


Toxin        


Download         Length: 94 a.a.        Molecular weight: 10746.26 Da        Isoelectric Point: 10.5447

>T266026 WP_277729574.1 NZ_CP113783:1776343-1776624 [Pseudoxanthomonas sp. SE1]
VIRDFADKEAEKVWNGTPSRRLPADMQAVARRKLRMLNNAATLDDLRIPPANRLEVLKGDRKGQHSIRINDQWRVCFRWK
GGDAHGVDIVDYH

Download         Length: 282 bp


Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10401.00 Da        Isoelectric Point: 6.4664

>AT266026 WP_093297534.1 NZ_CP113783:1776648-1776938 [Pseudoxanthomonas sp. SE1]
MKTLPNIHPGEVLLEEFLLPMGISQNALARAADVPPRRINEIVLGKRGVTADTAVRLAAALGTSERFWLGLQADYDLEEA
HRSLGAAVSRIERIAA

Download         Length: 291 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References