Detailed information of TA system TA026593

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1884295..1884475
• Replicon: chromosome
• Accession: NC_017337
• Organism: Staphylococcus aureus subsp. aureus ED133

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: SAOV_RS15340
• Protein ID: WP_001801861.1
• Coordinates: 1884295..1884390 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1884418..1884475 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAOV_RS09335	1879699..1880325	+	627	WP_000669034.1	hypothetical protein	-
SAOV_RS09340	1880366..1880707	+	342	WP_000627544.1	DUF3969 family protein	-
SAOV_RS09345	1880808..1881380	+	573	WP_000414210.1	hypothetical protein	-
SAOV_RS09350	1881756..1882592	+	837	WP_000190484.1	ABC transporter ATP-binding protein	-
SAOV_RS09360	1883398..1883844	-	447	WP_000747806.1	DUF1433 domain-containing protein	-
SAOV_RS15340	1884295..1884390	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1884418..1884475	-	58	-	-	Antitoxin
SAOV_RS09365	1884513..1884614	+	102	WP_001791232.1	hypothetical protein	-
SAOV_RS14985	1884600..1884779	-	180	Protein_1804	transposase	-
SAOV_RS09370	1884967..1885341	-	375	WP_000695817.1	DUF1433 domain-containing protein	-
SAOV_RS09375	1885331..1885711	-	381	WP_001035978.1	DUF1433 domain-containing protein	-
SAOV_RS09380	1885919..1886359	-	441	WP_000759945.1	DUF1433 domain-containing protein	-
SAOV_RS09385	1886404..1888017	+	1614	WP_000926709.1	hypothetical protein	-
SAOV_RS09390	1888032..1888331	+	300	WP_000095391.1	WXG100 family type VII secretion target	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T26593 WP_001801861.1 NC_017337:1884295-1884390 [Staphylococcus aureus subsp. aureus ED133]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T26593 NC_017337:1884295-1884390 [Staphylococcus aureus subsp. aureus ED133]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT26593 NC_017337:c1884475-1884418 [Staphylococcus aureus subsp. aureus ED133]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin