265856

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) HipBST/HipA(toxin)
Location 4788481..4789832 Replicon chromosome
Accession NZ_CP113504
Organism Pectobacterium brasiliense strain 21PCA_AGRO2

Toxin (Protein)


Gene name HipT Uniprot ID -
Locus tag OWC53_RS21955 Protein ID WP_268197954.1
Coordinates 4788792..4789832 (+) Length 347 a.a.

Antitoxin (Protein)


Gene name HipS Uniprot ID -
Locus tag OWC53_RS21950 Protein ID WP_039528006.1
Coordinates 4788481..4788795 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OWC53_RS21925 (OWC53_21910) 4784302..4785336 + 1035 WP_268197951.1 putative FMN-dependent luciferase-like monooxygenase -
OWC53_RS21930 (OWC53_21915) 4785333..4786466 + 1134 WP_268197952.1 alkylhydroperoxidase domain protein -
OWC53_RS21935 (OWC53_21920) 4786523..4787035 - 513 WP_268198909.1 phenolic acid decarboxylase -
OWC53_RS21940 (OWC53_21925) 4787135..4788007 + 873 WP_268197953.1 LysR family transcriptional regulator -
OWC53_RS21945 (OWC53_21930) 4788170..4788496 + 327 WP_014913674.1 helix-turn-helix domain-containing protein -
OWC53_RS21950 (OWC53_21935) 4788481..4788795 + 315 WP_039528006.1 HipA N-terminal domain-containing protein Antitoxin
OWC53_RS21955 (OWC53_21940) 4788792..4789832 + 1041 WP_268197954.1 HipA domain-containing protein Toxin
OWC53_RS21960 (OWC53_21945) 4789892..4790515 - 624 WP_039284934.1 LysE family translocator -
OWC53_RS21965 (OWC53_21950) 4790783..4791538 + 756 WP_110163156.1 thiol:disulfide interchange protein DsbG -
OWC53_RS21970 (OWC53_21955) 4791572..4792477 - 906 WP_268197955.1 siderophore-interacting protein -
OWC53_RS21975 (OWC53_21960) 4792732..4792983 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
OWC53_RS21980 (OWC53_21965) 4792980..4793267 + 288 WP_015842269.1 type II toxin-antitoxin system RelE/ParE family toxin -
OWC53_RS21985 (OWC53_21970) 4793371..4794723 - 1353 WP_205559960.1 glutathione-disulfide reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(57-307)

Antitoxin

HipA, N-terminal subdomain 1

(5-98)


Sequences

Toxin        


Download         Length: 347 a.a.        Molecular weight: 39628.67 Da        Isoelectric Point: 6.6652

>T265856 WP_268197954.1 NZ_CP113504:4788792-4789832 [Pectobacterium brasiliense]
MTRCRILLTPLTHEEEIATGYSRKGLKHLAGKMHTSPDLRFTRQQFMHDLPQAQKGMSISGYQPKIQLVLEEQAFTVVDH
QGLYILKPSPIEFPHLAENEHATMTLMARLGFAVPPHGLLRFKPEQADDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKIHTDGRQYVSYERLALFLSKHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLMHSRSGQLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADFLKEAKCVESTYRDSFMP
ADAIETTLRCYRHRLNLMSILDAERI

Download         Length: 1041 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11899.72 Da        Isoelectric Point: 9.2317

>AT265856 WP_039528006.1 NZ_CP113504:4788481-4788795 [Pectobacterium brasiliense]
MRRQVKVYLYGVHIGQLSQDDEGYLFEYKKSYIGPPLSLSLPIQTGTFRSKILPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKS

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References