265845

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 560008..560510 Replicon chromosome
Accession NZ_CP113504
Organism Pectobacterium brasiliense strain 21PCA_AGRO2

Toxin (Protein)


Gene name yoeB Uniprot ID A0A7W2E5L4
Locus tag OWC53_RS02610 Protein ID WP_039282578.1
Coordinates 560008..560262 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A7W2E625
Locus tag OWC53_RS02615 Protein ID WP_039324900.1
Coordinates 560259..560510 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OWC53_RS02590 (OWC53_02585) 555424..556263 + 840 WP_039522436.1 HTH-type transcriptional activator RhaS -
OWC53_RS02595 (OWC53_02590) 556288..557142 + 855 WP_039279287.1 helix-turn-helix domain-containing protein -
OWC53_RS02600 (OWC53_02595) 557336..558664 - 1329 WP_039522439.1 AAA family ATPase -
OWC53_RS02605 (OWC53_02600) 558661..559632 - 972 WP_039522442.1 reverse transcriptase domain-containing protein -
OWC53_RS02610 (OWC53_02605) 560008..560262 - 255 WP_039282578.1 Txe/YoeB family addiction module toxin Toxin
OWC53_RS02615 (OWC53_02610) 560259..560510 - 252 WP_039324900.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
OWC53_RS02620 (OWC53_02615) 560586..562295 - 1710 WP_039522445.1 ABC transporter ATP-binding protein -
OWC53_RS02625 (OWC53_02620) 562292..563158 - 867 WP_010285293.1 ABC transporter permease -
OWC53_RS02630 (OWC53_02625) 563151..564110 - 960 WP_039522448.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10229.79 Da        Isoelectric Point: 8.0353

>T265845 WP_039282578.1 NZ_CP113504:c560262-560008 [Pectobacterium brasiliense]
VKLIWSEEAWEDYLYWQDIDKRMVKKINELIKETRRTPFEGKGKPEPLKHNLAGFWSRRITEEHRLVYAITDDAMMIAAC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9367.64 Da        Isoelectric Point: 4.6119

>AT265845 WP_039324900.1 NZ_CP113504:c560510-560259 [Pectobacterium brasiliense]
MRTISYSEARQNLSATMMKTVEDRAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANAKRLMNSIESLKAGNGEERD
IIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7W2E5L4

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E625

References