265841

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 432902..433626 Replicon chromosome
Accession NZ_CP113504
Organism Pectobacterium brasiliense strain 21PCA_AGRO2

Toxin (Protein)


Gene name higB Uniprot ID A0A7V8TLN0
Locus tag OWC53_RS01995 Protein ID WP_039504225.1
Coordinates 432902..433213 (+) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OWC53_RS02000 Protein ID WP_039504227.1
Coordinates 433210..433626 (+) Length 139 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OWC53_RS01975 (OWC53_01975) 428831..430387 - 1557 WP_039504219.1 carbohydrate porin -
OWC53_RS01980 (OWC53_01980) 430586..431509 - 924 WP_205532751.1 aminoimidazole riboside kinase -
OWC53_RS01985 (OWC53_01985) 431834..432022 + 189 WP_039504221.1 hypothetical protein -
OWC53_RS01990 (OWC53_01990) 432192..432743 + 552 WP_268198113.1 polymer-forming cytoskeletal protein -
OWC53_RS01995 (OWC53_01995) 432902..433213 + 312 WP_039504225.1 type II toxin-antitoxin system HigB family toxin Toxin
OWC53_RS02000 (OWC53_02000) 433210..433626 + 417 WP_039504227.1 helix-turn-helix domain-containing protein Antitoxin
OWC53_RS02005 (OWC53_02005) 433765..434136 - 372 WP_039279503.1 helix-turn-helix transcriptional regulator -
OWC53_RS02010 (OWC53_02010) 434211..434471 - 261 WP_039279236.1 type II toxin-antitoxin system RelE/ParE family toxin -
OWC53_RS02015 (OWC53_02015) 434773..435231 + 459 WP_014913932.1 hypothetical protein -
OWC53_RS02020 (OWC53_02020) 435307..436659 - 1353 WP_268198115.1 pyridoxal-dependent decarboxylase -
OWC53_RS02025 (OWC53_02025) 436714..437970 - 1257 WP_268198116.1 MFS transporter -
OWC53_RS02030 (OWC53_02030) 438124..438570 + 447 WP_014913935.1 helix-turn-helix domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 104 a.a.        Molecular weight: 12406.28 Da        Isoelectric Point: 10.0380

>T265841 WP_039504225.1 NZ_CP113504:432902-433213 [Pectobacterium brasiliense]
MHVISRAPFDTATTQFPNQAAALADLYRVIKREMYATPDDMKKRFPSLDRMKYREKWWVIDIGGGHLRVMFFADFERGKI
FIKHITSHAEYDRLTEYYRRNKE

Download         Length: 312 bp


Antitoxin


Download         Length: 139 a.a.        Molecular weight: 15405.66 Da        Isoelectric Point: 4.6581

>AT265841 WP_039504227.1 NZ_CP113504:433210-433626 [Pectobacterium brasiliense]
MMYADAIKAANNLTSIVPFLGGSTSRKDYEDALKLTEYLIESEPDSPLIDMLTAKIDKYENDAPEFAAFNERIKALPAGI
ALLRVLMDQHQLTQSDFEAEIGKKSLVSRILNGERTLTLDHMRALAKRFDIPVSAFVD

Download         Length: 417 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7V8TLN0


Antitoxin

Source ID Structure

References