Detailed information of TA system TA026577

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 1079044..1079293
• Replicon: chromosome
• Accession: NC_017333
• Organism: Staphylococcus aureus subsp. aureus ST398

Toxin (Protein)

• Gene name: SprG2
• Uniprot ID: -
• Locus tag: SAPIG_RS05340
• Protein ID: WP_000623369.1
• Coordinates: 1079044..1079151 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprF2
Locus tag	-
Coordinates	1079146..1079293 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SAPIG_RS05315	1075718..1076287	-	570	WP_000287260.1	competence protein ComK	-
SAPIG_RS05320	1076497..1076715	+	219	WP_000876826.1	IDEAL domain-containing protein	-
SAPIG_RS05325	1076796..1077782	-	987	WP_000668814.1	lipoate--protein ligase	-
SAPIG_RS05330	1077981..1078157	+	177	WP_000214898.1	YkvS family protein	-
SAPIG_RS05335	1078172..1078774	+	603	WP_001033867.1	CPBP family intramembrane metalloprotease	-
SAPIG_RS05340	1079044..1079151	+	108	WP_000623369.1	putative holin-like toxin	Toxin
-	1079146..1079293	-	148	-	-	Antitoxin
SAPIG_RS05345	1079786..1080070	+	285	WP_000790905.1	lactococcin 972 family bacteriocin	-
SAPIG_RS05350	1080114..1082078	+	1965	WP_000870811.1	bacteriocin-associated integral membrane family protein	-
SAPIG_RS05355	1082081..1082401	+	321	WP_000668623.1	YxeA family protein	-
SAPIG_RS05360	1082398..1083039	+	642	WP_000571192.1	ABC transporter ATP-binding protein	-
SAPIG_RS15015	1083127..1083417	-	291	WP_001796515.1	hypothetical protein	-
SAPIG_RS15020	1083507..1083695	+	189	WP_157958947.1	poly(glycerol-phosphate) alpha-glucosyltransferase	-
SAPIG_RS05370	1083784..1084140	-	357	WP_000766009.1	DoxX family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (3-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3801.69 Da
• Isoelectric Point: 10.8004

>T26577 WP_000623369.1 NC_017333:1079044-1079151 [Staphylococcus aureus subsp. aureus ST398]
VISIANALHLMLSFGMFIVTFIGVVVAIINLNNKK

Nucleotide

• Length: 108 bp

>T26577 NC_017333:1079044-1079151 [Staphylococcus aureus subsp. aureus ST398]
GTGATATCTATTGCAAATGCATTACATTTAATGTTAAGTTTCGGTATGTTTATCGTCACTTTCATTGGTGTAGTAGTCGC
AATAATTAATTTAAACAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 148 bp

>AT26577 NC_017333:c1079293-1079146 [Staphylococcus aureus subsp. aureus ST398]
CAATTAAATAAAAGATATGTTACTATAAAAATGTAAAAAGACGACATGCAGTAACATGTCGCCTAATGAGCCCGTTAAAA
AGACGGTGACTAAATGAGATTTGCTTTAACCATCATTCGTTGTCAAAGTTTTGAAATGATGGTTATTT

Structures

Antitoxin