Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2708065..2708249 Replicon chromosome
Accession NC_017331
Organism Staphylococcus aureus subsp. aureus TW20

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag SATW20_RS14055 Protein ID WP_000482650.1
Coordinates 2708142..2708249 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2708065..2708125 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SATW20_RS14030 2703595..2703762 - 168 WP_001790576.1 hypothetical protein -
SATW20_RS14040 2703993..2705726 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
SATW20_RS14045 2705751..2707514 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
- 2708065..2708125 + 61 - - Antitoxin
SATW20_RS14055 2708142..2708249 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
SATW20_RS14060 2708383..2708769 - 387 WP_000779358.1 flippase GtxA -
SATW20_RS14065 2709037..2710179 + 1143 WP_001176863.1 glycerate kinase -
SATW20_RS14070 2710239..2710898 + 660 WP_000831298.1 membrane protein -
SATW20_RS14075 2711080..2712291 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SATW20_RS14080 2712414..2712887 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T26569 WP_000482650.1 NC_017331:c2708249-2708142 [Staphylococcus aureus subsp. aureus TW20]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T26569 NC_017331:c2708249-2708142 [Staphylococcus aureus subsp. aureus TW20]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT26569 NC_017331:2708065-2708125 [Staphylococcus aureus subsp. aureus TW20]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References