Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | yefM-yoeB (relBE)/Txe-RelB |
| Location | 2682713..2683230 | Replicon | chromosome |
| Accession | NC_017331 | ||
| Organism | Staphylococcus aureus subsp. aureus TW20 | ||
Toxin (Protein)
| Gene name | yoeB | Uniprot ID | T1YC79 |
| Locus tag | SATW20_RS13900 | Protein ID | WP_000113262.1 |
| Coordinates | 2682713..2682979 (-) | Length | 89 a.a. |
Antitoxin (Protein)
| Gene name | yefM | Uniprot ID | T1YB60 |
| Locus tag | SATW20_RS13905 | Protein ID | WP_000584499.1 |
| Coordinates | 2682979..2683230 (-) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SATW20_RS13875 | 2678139..2678675 | - | 537 | WP_000169317.1 | GNAT family N-acetyltransferase | - |
| SATW20_RS13880 | 2678908..2679732 | - | 825 | WP_000572040.1 | formate/nitrite transporter family protein | - |
| SATW20_RS13885 | 2679949..2680131 | - | 183 | WP_000230294.1 | hypothetical protein | - |
| SATW20_RS13890 | 2680215..2680682 | - | 468 | WP_000153344.1 | SRPBCC domain-containing protein | - |
| SATW20_RS13895 | 2680868..2682418 | - | 1551 | WP_000727762.1 | zinc ABC transporter substrate-binding lipoprotein AdcA | - |
| SATW20_RS16850 | 2682607..2682678 | - | 72 | Protein_2647 | hypothetical protein | - |
| SATW20_RS13900 | 2682713..2682979 | - | 267 | WP_000113262.1 | Txe/YoeB family addiction module toxin | Toxin |
| SATW20_RS13905 | 2682979..2683230 | - | 252 | WP_000584499.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| SATW20_RS13910 | 2683395..2683496 | - | 102 | WP_001791744.1 | hypothetical protein | - |
| SATW20_RS13915 | 2683503..2684102 | - | 600 | WP_000162813.1 | DsbA family protein | - |
| SATW20_RS13920 | 2684121..2684483 | - | 363 | WP_000819843.1 | DUF4467 domain-containing protein | - |
| SATW20_RS13925 | 2684738..2685988 | + | 1251 | WP_001012222.1 | FemA/FemB family glycyltransferase FmhA | - |
| SATW20_RS13930 | 2686085..2686816 | - | 732 | WP_000615461.1 | amino acid ABC transporter ATP-binding protein | - |
| SATW20_RS13935 | 2686813..2687532 | - | 720 | WP_000479576.1 | amino acid ABC transporter permease | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10437.95 Da Isoelectric Point: 9.9143
>T26568 WP_000113262.1 NC_017331:c2682979-2682713 [Staphylococcus aureus subsp. aureus TW20]
MARLNITFSPQAFEDYKYFQQNDKKMVKKINELLKSIDRNGALEGIGKPEKLKSNLTGYYSRRINHEHRLVYTVDDNHIK
IASCKYHY
MARLNITFSPQAFEDYKYFQQNDKKMVKKINELLKSIDRNGALEGIGKPEKLKSNLTGYYSRRINHEHRLVYTVDDNHIK
IASCKYHY
Download Length: 267 bp
>T26568 NC_017331:c2682979-2682713 [Staphylococcus aureus subsp. aureus TW20]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9433.60 Da Isoelectric Point: 4.3407
>AT26568 WP_000584499.1 NC_017331:c2683230-2682979 [Staphylococcus aureus subsp. aureus TW20]
MIIKNYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESDYNSMMETLYLQQNPNNAEHLAQSIADLERGKTITKD
IDV
MIIKNYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESDYNSMMETLYLQQNPNNAEHLAQSIADLERGKTITKD
IDV
Download Length: 252 bp
>AT26568 NC_017331:c2683230-2682979 [Staphylococcus aureus subsp. aureus TW20]
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|