Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 242907..243541 Replicon chromosome
Accession NZ_CP113343
Organism Arthrobacter sp. MMS18-M83

Toxin (Protein)


Gene name HigB2 Uniprot ID -
Locus tag OW521_RS01135 Protein ID WP_268022210.1
Coordinates 243212..243541 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name HigA2 Uniprot ID -
Locus tag OW521_RS01130 Protein ID WP_268022208.1
Coordinates 242907..243212 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OW521_RS01105 (OW521_01105) 238461..240062 + 1602 WP_268022201.1 TIGR04141 family sporadically distributed protein -
OW521_RS01110 (OW521_01110) 240334..240741 - 408 WP_268022203.1 GNAT family N-acetyltransferase -
OW521_RS01115 (OW521_01115) 240794..241003 - 210 WP_268026132.1 hypothetical protein -
OW521_RS01120 (OW521_01120) 241016..241219 - 204 Protein_223 LysR family transcriptional regulator -
OW521_RS01125 (OW521_01125) 241445..241978 - 534 WP_268022206.1 HIRAN domain-containing protein -
OW521_RS01130 (OW521_01130) 242907..243212 - 306 WP_268022208.1 XRE family transcriptional regulator Antitoxin
OW521_RS01135 (OW521_01135) 243212..243541 - 330 WP_268022210.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OW521_RS01140 (OW521_01140) 243633..243833 - 201 WP_268022212.1 hypothetical protein -
OW521_RS01145 (OW521_01145) 243970..244098 - 129 WP_268022214.1 hypothetical protein -
OW521_RS01150 (OW521_01150) 244485..245891 - 1407 WP_268022216.1 tetratricopeptide repeat protein -
OW521_RS01155 (OW521_01155) 245893..247170 - 1278 WP_268022218.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(4-98)

Antitoxin

HigA2-like, helix-turn-helix domain

(32-92)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12307.03 Da        Isoelectric Point: 6.7278

>T265677 WP_268022210.1 NZ_CP113343:c243541-243212 [Arthrobacter sp. MMS18-M83]
VESWLLGLDQDSYEQVIAALELLAERGPQLGRPLVDTVVRSRHRNMKELRPGSSGRSELRILFAFDPERHAILLVAGDKA
GNWSKWYKTNIPIADDLFDDHLRILKGGS

Download         Length: 330 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11617.28 Da        Isoelectric Point: 6.2455

>AT265677 WP_268022208.1 NZ_CP113343:c243212-242907 [Arthrobacter sp. MMS18-M83]
MAKTIEEMLAERTVDRVAVDAHKKLLLDEVRAYRLRELREASELTQVELAARLHVSQNRVSRIEHGDIDRAQVDTLRKYV
EAVGGRLRVEVELGDERIQIA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References