Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2417656..2417919 Replicon chromosome
Accession NC_017331
Organism Staphylococcus aureus subsp. aureus TW20

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SATW20_RS12480 Protein ID WP_001802298.1
Coordinates 2417815..2417919 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2417656..2417820 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SATW20_RS12460 2413839..2414504 - 666 WP_001024094.1 SDR family oxidoreductase -
SATW20_RS12465 2414656..2414976 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
SATW20_RS12470 2414978..2415958 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
SATW20_RS12475 2416224..2417315 + 1092 WP_000495671.1 lytic regulatory protein -
- 2417656..2417820 + 165 - - Antitoxin
SATW20_RS12480 2417815..2417919 - 105 WP_001802298.1 hypothetical protein Toxin
SATW20_RS16840 2418080..2418563 - 484 Protein_2381 recombinase family protein -
SATW20_RS12490 2418606..2419742 - 1137 WP_000115564.1 SAP domain-containing protein -
SATW20_RS12495 2420031..2420123 + 93 WP_001790138.1 hypothetical protein -
SATW20_RS12500 2420828..2421685 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
SATW20_RS12505 2421753..2422535 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T26566 WP_001802298.1 NC_017331:c2417919-2417815 [Staphylococcus aureus subsp. aureus TW20]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T26566 NC_017331:c2417919-2417815 [Staphylococcus aureus subsp. aureus TW20]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT26566 NC_017331:2417656-2417820 [Staphylococcus aureus subsp. aureus TW20]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References