Detailed information of TA system TA026564

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2417640..2417919
• Replicon: chromosome
• Accession: NC_017331
• Organism: Staphylococcus aureus subsp. aureus TW20

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: SATW20_RS12480
• Protein ID: WP_001802298.1
• Coordinates: 2417815..2417919 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2417640..2417819 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SATW20_RS12460	2413839..2414504	-	666	WP_001024094.1	SDR family oxidoreductase	-
SATW20_RS12465	2414656..2414976	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
SATW20_RS12470	2414978..2415958	+	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
SATW20_RS12475	2416224..2417315	+	1092	WP_000495671.1	lytic regulatory protein	-
-	2417640..2417819	+	180	-	-	Antitoxin
SATW20_RS12480	2417815..2417919	-	105	WP_001802298.1	hypothetical protein	Toxin
SATW20_RS16840	2418080..2418563	-	484	Protein_2381	recombinase family protein	-
SATW20_RS12490	2418606..2419742	-	1137	WP_000115564.1	SAP domain-containing protein	-
SATW20_RS12495	2420031..2420123	+	93	WP_001790138.1	hypothetical protein	-
SATW20_RS12500	2420828..2421685	-	858	WP_000370924.1	Cof-type HAD-IIB family hydrolase	-
SATW20_RS12505	2421753..2422535	-	783	WP_000908176.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T26564 WP_001802298.1 NC_017331:c2417919-2417815 [Staphylococcus aureus subsp. aureus TW20]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T26564 NC_017331:c2417919-2417815 [Staphylococcus aureus subsp. aureus TW20]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 180 bp

>AT26564 NC_017331:2417640-2417819 [Staphylococcus aureus subsp. aureus TW20]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin