Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 3999259..3999874 Replicon chromosome
Accession NZ_CP113163
Organism Citrobacter braakii strain LBA3

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag MKJ05_RS19025 Protein ID WP_267587718.1
Coordinates 3999608..3999874 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag MKJ05_RS19020 Protein ID WP_114681422.1
Coordinates 3999259..3999555 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKJ05_RS19005 (MKJ05_19005) 3996434..3996907 - 474 WP_016154802.1 transcription elongation factor GreB -
MKJ05_RS19010 (MKJ05_19010) 3997133..3997852 + 720 WP_001157751.1 two-component system response regulator OmpR -
MKJ05_RS19015 (MKJ05_19015) 3997849..3999201 + 1353 WP_114681423.1 two-component system sensor histidine kinase EnvZ -
MKJ05_RS19020 (MKJ05_19020) 3999259..3999555 - 297 WP_114681422.1 NadS family protein Antitoxin
MKJ05_RS19025 (MKJ05_19025) 3999608..3999874 - 267 WP_267587718.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MKJ05_RS19030 (MKJ05_19030) 4000049..4001671 - 1623 WP_114681420.1 phosphoenolpyruvate carboxykinase (ATP) -
MKJ05_RS19035 (MKJ05_19035) 4002050..4003768 + 1719 WP_267587721.1 DUF4153 domain-containing protein -
MKJ05_RS19040 (MKJ05_19040) 4003851..4004729 - 879 WP_103769633.1 Hsp33 family molecular chaperone HslO -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(26-86)

Antitoxin

Cro/C1-type helix-turn-helix domain

(39-75)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10133.51 Da        Isoelectric Point: 8.4537

>T265442 WP_267587718.1 NZ_CP113163:c3999874-3999608 [Citrobacter braakii]
MPDDEFRAFQEALIDNPEAGDTIAGTGGFRKIRWSRSGMGKRSGIRVIYYNVSRNGRIYLALLYPKNEQDDLTEEQRKVL
KHLSDMLI

Download         Length: 267 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11216.03 Da        Isoelectric Point: 7.2052

>AT265442 WP_114681422.1 NZ_CP113163:c3999555-3999259 [Citrobacter braakii]
MKDELFADLLASAEEMVRIEKGEETPKPEHVHTFSEIDVKAIREATGLRQQDFAIAVGVSYDLVKSWEMKRRQPTGAPRK
LLLLIQRNPFIINQLKAI

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References