Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2506581..2506843 Replicon chromosome
Accession NZ_CP113105
Organism Staphylococcus aureus strain BIAI 117

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag OSZ56_RS12180 Protein ID WP_073392962.1
Coordinates 2506581..2506685 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF2
Locus tag -
Coordinates 2506680..2506843 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSZ56_RS12165 2503377..2504159 + 783 WP_000908186.1 ABC transporter ATP-binding protein -
OSZ56_RS12170 2504227..2505084 + 858 WP_000370937.1 HAD family hydrolase -
OSZ56_RS12175 2505743..2505901 - 159 WP_078171426.1 integrase -
OSZ56_RS12180 2506581..2506685 + 105 WP_073392962.1 hypothetical protein Toxin
- 2506680..2506843 - 164 - - Antitoxin
OSZ56_RS12190 2507370..2509016 + 1647 WP_000277709.1 IS1182-like element ISSau3 family transposase -
OSZ56_RS12195 2509045..2510136 - 1092 WP_064127636.1 hypothetical protein -
OSZ56_RS12200 2510402..2511382 - 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
OSZ56_RS12205 2511384..2511704 - 321 WP_053862123.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2507370..2509016 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T265410 WP_073392962.1 NZ_CP113105:2506581-2506685 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp


Antitoxin


Download         Length: 164 bp

>AT265410 NZ_CP113105:c2506843-2506680 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References