Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2220854..2221038 Replicon chromosome
Accession NZ_CP113105
Organism Staphylococcus aureus strain BIAI 117

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag OSZ56_RS10675 Protein ID WP_000482647.1
Coordinates 2220854..2220961 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2220978..2221038 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSZ56_RS10650 2216216..2216689 + 474 WP_000456496.1 GyrI-like domain-containing protein -
OSZ56_RS10655 2216812..2218023 - 1212 WP_001191919.1 multidrug effflux MFS transporter -
OSZ56_RS10660 2218205..2218864 - 660 WP_000831298.1 membrane protein -
OSZ56_RS10665 2218924..2220066 - 1143 Protein_2065 glycerate kinase -
OSZ56_RS10670 2220334..2220720 + 387 WP_000779351.1 flippase GtxA -
OSZ56_RS10675 2220854..2220961 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2220978..2221038 - 61 - - Antitoxin
OSZ56_RS10680 2221609..2223372 + 1764 WP_001064829.1 ABC transporter ATP-binding protein -
OSZ56_RS10685 2223397..2225130 + 1734 WP_000486505.1 ABC transporter ATP-binding protein -
OSZ56_RS10690 2225361..2225528 + 168 Protein_2070 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T265408 WP_000482647.1 NZ_CP113105:2220854-2220961 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp


Antitoxin


Download         Length: 61 bp

>AT265408 NZ_CP113105:c2221038-2220978 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7


Antitoxin

Download structure file

References