Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 594132..594832 Replicon chromosome
Accession NZ_CP113096
Organism Pseudomonas citronellolis strain G5Li.T10

Toxin (Protein)


Gene name mqsR Uniprot ID W5IYY9
Locus tag OSS47_RS02720 Protein ID WP_009615994.1
Coordinates 594536..594832 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A1A9KI60
Locus tag OSS47_RS02715 Protein ID WP_043314031.1
Coordinates 594132..594533 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSS47_RS02700 (OSS47_02700) 589785..590519 + 735 WP_043314028.1 amino acid ABC transporter ATP-binding protein -
OSS47_RS02705 (OSS47_02705) 590628..592514 + 1887 WP_043314029.1 sensor histidine kinase -
OSS47_RS02710 (OSS47_02710) 592562..593839 + 1278 WP_236695168.1 sigma-54 dependent transcriptional regulator -
OSS47_RS02715 (OSS47_02715) 594132..594533 - 402 WP_043314031.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
OSS47_RS02720 (OSS47_02720) 594536..594832 - 297 WP_009615994.1 type II toxin-antitoxin system MqsR family toxin Toxin
OSS47_RS02725 (OSS47_02725) 594959..595411 + 453 WP_009615993.1 hypothetical protein -
OSS47_RS02730 (OSS47_02730) 595523..595753 + 231 WP_009615992.1 hypothetical protein -
OSS47_RS02735 (OSS47_02735) 595919..596158 + 240 WP_009615991.1 hypothetical protein -
OSS47_RS02740 (OSS47_02740) 596166..596777 - 612 WP_043273198.1 class I SAM-dependent methyltransferase -
OSS47_RS02745 (OSS47_02745) 596973..597695 + 723 WP_009615989.1 GntR family transcriptional regulator -
OSS47_RS02750 (OSS47_02750) 597692..598576 + 885 WP_009615988.1 methylisocitrate lyase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10866.62 Da        Isoelectric Point: 9.5238

>T265386 WP_009615994.1 NZ_CP113096:c594832-594536 [Pseudomonas citronellolis]
MEKSTPHCRLDRVKSLLAQGRVRATYSALSGGAALGLDFAGMLAVIEALAPRDFYKSMTTHADHRVWQDVYRPSTAVGRI
YLKLTVIDDVLVVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14458.70 Da        Isoelectric Point: 7.0843

>AT265386 WP_043314031.1 NZ_CP113096:c594533-594132 [Pseudomonas citronellolis]
MKCPLCGGAELLHETRDLPYAYKGESTLITAVRGEFCPACGEAVLDADESARVNAQMLAFNKRVNASMVDPGFIAAVRKK
LALDQREAAEIFGGGVNAFSRYENGKTRPPLALVKLLKVLDRHPELLEEVRAG

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB W5IYY9

Antitoxin

Source ID Structure
AlphaFold DB A0A1A9KI60

References