Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 167129..167631 Replicon plasmid unnamed2
Accession NZ_CP113087
Organism Pantoea agglomerans strain AB378

Toxin (Protein)


Gene name yoeB Uniprot ID A0A8X8DPE2
Locus tag OSE17_RS22125 Protein ID WP_010256862.1
Coordinates 167377..167631 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A349IE86
Locus tag OSE17_RS22120 Protein ID WP_010256861.1
Coordinates 167129..167380 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSE17_RS22105 (OSE17_22105) 162831..164282 + 1452 WP_191914321.1 flagellin -
OSE17_RS22110 (OSE17_22110) 164624..165937 + 1314 WP_010256858.1 CitMHS family transporter -
OSE17_RS22115 (OSE17_22115) 166105..166944 + 840 WP_159227283.1 MBL fold metallo-hydrolase -
OSE17_RS22120 (OSE17_22120) 167129..167380 + 252 WP_010256861.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
OSE17_RS22125 (OSE17_22125) 167377..167631 + 255 WP_010256862.1 Txe/YoeB family addiction module toxin Toxin
OSE17_RS22130 (OSE17_22130) 167687..170233 - 2547 WP_172608087.1 excinuclease ABC subunit UvrA -
OSE17_RS22135 (OSE17_22135) 170897..171355 + 459 WP_191914341.1 hypothetical protein -
OSE17_RS22140 (OSE17_22140) 171376..171642 + 267 WP_229518749.1 DUF1493 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..183838 183838
- flank IS/Tn - - 171853..171978 125


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9782.16 Da        Isoelectric Point: 9.3799

>T265385 WP_010256862.1 NZ_CP113087:167377-167631 [Pantoea agglomerans]
VKLTWSAEAWEDYLYWQDADKKTVKKINELLKDASRTPFEGKGKPEPLKHNLAGFWSRRITAEHRLVYAVSGDALLIASC
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9339.48 Da        Isoelectric Point: 4.4155

>AT265385 WP_010256861.1 NZ_CP113087:167129-167380 [Pantoea agglomerans]
MRAISYSEARQNLSATMVQTVEDKAPVLITRQNGESCVLMSLEEYNSLEETAYLLRSPKNARRLMDSIESLQSGNGTDRD
IIE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A349IE86

References