Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 105880..106701 Replicon plasmid unnamed1
Accession NZ_CP113086
Organism Pantoea agglomerans strain AB378

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag OSE17_RS19220 Protein ID WP_010247344.1
Coordinates 105880..106350 (-) Length 157 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag OSE17_RS19225 Protein ID WP_033768537.1
Coordinates 106357..106701 (-) Length 115 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OSE17_RS19210 (OSE17_19210) 101205..103607 + 2403 WP_267713314.1 maltodextrin phosphorylase -
OSE17_RS19215 (OSE17_19215) 103616..105691 + 2076 WP_191914086.1 4-alpha-glucanotransferase -
OSE17_RS19220 (OSE17_19220) 105880..106350 - 471 WP_010247344.1 type II toxin-antitoxin system YhaV family toxin Toxin
OSE17_RS19225 (OSE17_19225) 106357..106701 - 345 WP_033768537.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
OSE17_RS19230 (OSE17_19230) 106800..106967 - 168 WP_244649673.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
OSE17_RS19235 (OSE17_19235) 107204..108142 - 939 WP_191914085.1 maltose operon protein MalM -
OSE17_RS19240 (OSE17_19240) 108245..109546 - 1302 WP_033760237.1 maltoporin -
OSE17_RS19245 (OSE17_19245) 109590..110699 - 1110 WP_031594250.1 maltose/maltodextrin ABC transporter ATP-binding protein MalK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..555125 555125


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-148)

Antitoxin

PrlF antitoxin

(15-113)


Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 18278.80 Da        Isoelectric Point: 8.9277

>T265381 WP_010247344.1 NZ_CP113086:c106350-105880 [Pantoea agglomerans]
MEDSTVINGWHVYVHPCFESQLIALTNEVELLRAKYPESYQRKATTKLLAAVFKVINSEICADPHQAKFRQGDTLGEQNK
HWFRAKFLMQYRLFFRFSEQHKTIILAWMNDAETKRAYGSKRDAYKVFSGMLHNGYPPDDWALLLKQSQDWANTNS

Download         Length: 471 bp

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12267.93 Da        Isoelectric Point: 4.3278

>AT265381 WP_033768537.1 NZ_CP113086:c106701-106357 [Pantoea agglomerans]
MGTLTHANISLRASSKLTARSQTTIPAAVRDAMNLQPGENIEYAVLPGGKVLITRQETVTDDDPVIASFLSFLAADIRNT
PANIKTLDRGLLTRITSLTEGMDVDLDAPLMDDE

Download         Length: 345 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References