Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2869899..2870081 Replicon chromosome
Accession NZ_CP113052
Organism Staphylococcus aureus strain Fizz

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag OS084_RS14435 Protein ID WP_001801861.1
Coordinates 2869899..2869994 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2870022..2870081 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS084_RS14395 2865559..2866185 + 627 Protein_2796 hypothetical protein -
OS084_RS14400 2866226..2866570 + 345 WP_000627551.1 DUF3969 family protein -
OS084_RS14405 2866668..2867219 + 552 WP_000414205.1 hypothetical protein -
OS084_RS14410 2867437..2868078 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
OS084_RS14415 2868192..2868377 - 186 WP_000809857.1 hypothetical protein -
OS084_RS14420 2868379..2868555 - 177 WP_000375476.1 hypothetical protein -
OS084_RS14425 2868566..2868949 - 384 WP_000070811.1 hypothetical protein -
OS084_RS14430 2869553..2869696 - 144 WP_001549059.1 transposase -
OS084_RS14435 2869899..2869994 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 2870022..2870081 - 60 - - Antitoxin
OS084_RS14440 2870117..2870218 + 102 WP_001791893.1 hypothetical protein -
OS084_RS14445 2870196..2870372 - 177 Protein_2806 transposase -
OS084_RS14450 2870566..2870943 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T265350 WP_001801861.1 NZ_CP113052:2869899-2869994 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

Antitoxin


Download         Length: 60 bp

>AT265350 NZ_CP113052:c2870081-2870022 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References