Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 618438..618622 Replicon chromosome
Accession NZ_CP113052
Organism Staphylococcus aureus strain Fizz

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag OS084_RS03480 Protein ID WP_000482650.1
Coordinates 618515..618622 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 618438..618498 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS084_RS03465 613968..614135 - 168 WP_001790576.1 hypothetical protein -
OS084_RS03470 614366..616099 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
OS084_RS03475 616124..617887 - 1764 WP_001064838.1 ABC transporter ATP-binding protein -
- 618438..618498 + 61 - - Antitoxin
OS084_RS03480 618515..618622 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
OS084_RS03485 618756..619142 - 387 WP_000779358.1 flippase GtxA -
OS084_RS03490 619410..620552 + 1143 WP_001176863.1 glycerate kinase -
OS084_RS03495 620612..621271 + 660 WP_000831298.1 membrane protein -
OS084_RS03500 621453..622664 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
OS084_RS03505 622787..623260 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T265347 WP_000482650.1 NZ_CP113052:c618622-618515 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT265347 NZ_CP113052:618438-618498 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References