Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-SprF3/-
Location 153714..154013 Replicon chromosome
Accession NZ_CP113052
Organism Staphylococcus aureus strain Fizz

Toxin (Protein)


Gene name txpA Uniprot ID Q2FWU9
Locus tag OS084_RS00960 Protein ID WP_011447039.1
Coordinates 153837..154013 (-) Length 59 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 153714..153769 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS084_RS00920 149045..149305 + 261 WP_001791826.1 hypothetical protein -
OS084_RS00925 149358..149708 - 351 WP_000702263.1 complement inhibitor SCIN-A -
OS084_RS00930 150393..150842 + 450 WP_000727649.1 chemotaxis-inhibiting protein CHIPS -
OS084_RS00935 150937..151272 - 336 Protein_147 SH3 domain-containing protein -
OS084_RS00940 151922..152413 - 492 WP_000919350.1 staphylokinase -
OS084_RS00945 152604..153359 - 756 WP_031785843.1 CHAP domain-containing protein -
OS084_RS00950 153371..153625 - 255 WP_000611512.1 phage holin -
OS084_RS00955 153677..153784 + 108 WP_001791821.1 hypothetical protein -
- 153706..153845 + 140 NuclAT_0 - -
- 153706..153845 + 140 NuclAT_0 - -
- 153706..153845 + 140 NuclAT_0 - -
- 153706..153845 + 140 NuclAT_0 - -
- 153714..153769 + 56 - - Antitoxin
OS084_RS00960 153837..154013 - 177 WP_011447039.1 type I toxin-antitoxin system toxin PepG1 Toxin
OS084_RS00965 154163..154459 - 297 WP_000539688.1 DUF2951 domain-containing protein -
OS084_RS00970 154517..154804 - 288 WP_001040261.1 hypothetical protein -
OS084_RS00975 154851..155003 - 153 WP_001153681.1 hypothetical protein -
OS084_RS00980 154993..158778 - 3786 WP_000582165.1 phage tail spike protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - scn / chp / sak / hlb / groEL 149358..205306 55948


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6849.45 Da        Isoelectric Point: 10.6777

>T265340 WP_011447039.1 NZ_CP113052:c154013-153837 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Download         Length: 177 bp

Antitoxin


Download         Length: 56 bp

>AT265340 NZ_CP113052:153714-153769 [Staphylococcus aureus]
AAAAAGGGCAACATGCGCAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 7NS1

Antitoxin

Download structure file

References