Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2152281..2152804 Replicon chromosome
Accession NZ_CP113051
Organism Staphylococcus aureus strain Viktor

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag OS088_RS11100 Protein ID WP_061838884.1
Coordinates 2152281..2152547 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag OS088_RS11105 Protein ID WP_154283974.1
Coordinates 2152547..2152804 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OS088_RS11080 (2147492) 2147492..2148679 - 1188 WP_000026189.1 MFS transporter -
OS088_RS11085 (2149073) 2149073..2149849 - 777 WP_154283971.1 iron export ABC transporter permease subunit FetB -
OS088_RS11090 (2149842) 2149842..2150504 - 663 WP_154283972.1 ATP-binding cassette domain-containing protein -
OS088_RS11095 (2150850) 2150850..2151926 - 1077 WP_154283973.1 M42 family metallopeptidase -
OS088_RS11100 (2152281) 2152281..2152547 - 267 WP_061838884.1 Txe/YoeB family addiction module toxin Toxin
OS088_RS11105 (2152547) 2152547..2152804 - 258 WP_154283974.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OS088_RS11110 (2153163) 2153163..2153618 + 456 WP_000732082.1 DUF1307 domain-containing protein -
OS088_RS11115 (2153786) 2153786..2155363 - 1578 WP_154283975.1 FMN-binding glutamate synthase family protein -
OS088_RS11120 (2155558) 2155558..2156307 + 750 WP_154284532.1 CPBP family lipoprotein N-acylation protein LnsB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10698.38 Da        Isoelectric Point: 10.1384

>T265338 WP_061838884.1 NZ_CP113051:c2152547-2152281 [Staphylococcus aureus]
MSNYTVKIKNSAKLDLKKIKHPYLKKTFIEIVETLKNDPYKITQSFEKLEPKYLERYSRRINHQHRVVYTVDDRNKEVLI
LSAWSHYD

Download         Length: 267 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9784.84 Da        Isoelectric Point: 4.4205

>AT265338 WP_154283974.1 NZ_CP113051:c2152804-2152547 [Staphylococcus aureus]
MIITSPTEARKHFYQLLKNVNNNHEPIYISGNNAENNAVIIGLEDWKSIQETMYLVSTGTMDKVREREKDNSGTTNIDDI
DWDNL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References